Dr. Gary Steinberg

Thank you, Andrew.

Pleasure to be here.

Sure.

So a stroke is like a heart attack of the brain.

It involves disruption of blood flow to the brain, either in the form of a blocked vessel or less likely a hemorrhage.

About 87% of strokes are due to a clot.

either forming in the brain artery itself or forming closer to the heart, in the heart or in the carotid artery and dislodging and blocking blood flow to the brain.

About 13% are caused by a hemorrhage, bursting of a blood vessel.

And that results in lack of oxygen and glucose being delivered to the brain cells.

And that ultimately causes death of tissue and disruption of bodily functions, neurologic function.

Sure.

Well, you might not know.

In many cases, you don't know.

And that's the problem.

You can have a predisposition, as you say, due to certain genes that are mutated or represented that predispose to clots.

And those clots can occur on the arterial side or the venous side.

The arterial side is what generally causes a stroke, an ischemic stroke.

On the venous side, you can sometimes have problems.

When you talk about flying, not moving your legs, developing clots in your legs, wearing compression boots, that's on the venous side.

And that can cause something like a deep vein thrombosis, which is not good because it can travel to the lung.