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Dr. Gary Steinberg

๐Ÿ‘ค Speaker
686 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

We can map it out on an MR scan.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And the way it's mapped out is we have the patient awake, talk to us when they do the scan.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And because there's a coupling between blood flow and the neuronal activity, when the speech area, the language area is stimulated by talking,

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

there's increased blood flow to that area, and we can see that on an MR scan.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

That's how the MR scan works.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

So we had some idea that this was very close, if not in the speech area, but the most accurate way of determining that is to operate on the patient with her awake.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

So what we did was we sedate the patient.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

We don't put a tube down and induce general anesthesia.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

We numb up the scalp.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

We take off a piece of bone after cutting the scalp, open the membrane covering the brain called the dura, and then we allow the patient to wake up more from the sedation.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And then what I did on this particular patient was to use a tiny stimulator, a little probe, and I can stimulate areas of her cortex with her awake and see if the stimulation impairs her ability to speak or understand language.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And quite surprisingly, there was no activity in the corridor that I chose.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

Sometimes when we see an area that

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

is involved with speech that's eloquent, we have to choose a different pathway to get to the underlying vascular problem.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And so that's what we did in this case.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

And she talked to us the entire case.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

She told us about her daughter, who was very involved in debate.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

and all of her successes while we were operating, while I was taking out this vascular malformation under 20 magnification with very special instruments.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

I use a laser now, which has a diameter of the fiber optic cable.

Huberman Lab
Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

The laser tip is 0.5 millimeters.