Dr. George Papanicolaou

So now I can find out there's enzymes that break down dopamine. In various parts of the brain, there's enzymes that are responsible for serotonin metabolism. So we look at those. And there can be patterns that can be associated or predispose somebody to a certain way of thinking or behaving or experiencing the world. In Claire's case, one of the blueprints I look at is called the COMT.

So now I can find out there's enzymes that break down dopamine. In various parts of the brain, there's enzymes that are responsible for serotonin metabolism. So we look at those. And there can be patterns that can be associated or predispose somebody to a certain way of thinking or behaving or experiencing the world. In Claire's case, one of the blueprints I look at is called the COMT.

So that COMT blueprint is basically responsible for breaking down dopamine in the prefrontal cortex. Dopamine is critical because it is the neurotransmitter responsible, as I said before, for cognition, learning, focus, attention, planning, which you call executive function, and self-regulation of emotion.

So that COMT blueprint is basically responsible for breaking down dopamine in the prefrontal cortex. Dopamine is critical because it is the neurotransmitter responsible, as I said before, for cognition, learning, focus, attention, planning, which you call executive function, and self-regulation of emotion.

So that COMT blueprint is basically responsible for breaking down dopamine in the prefrontal cortex. Dopamine is critical because it is the neurotransmitter responsible, as I said before, for cognition, learning, focus, attention, planning, which you call executive function, and self-regulation of emotion.

It plays a big role, although there are other parts of the brain, newer transmitters that do that as well. In her case, her gene breaks down dopamine very slowly. So she's predisposed to having a high level of dopamine in her brain at baseline, which is actually a good thing. And then she has another gene, the MAO gene. It also breaks down dopamine. And that one was also working very slow.

It plays a big role, although there are other parts of the brain, newer transmitters that do that as well. In her case, her gene breaks down dopamine very slowly. So she's predisposed to having a high level of dopamine in her brain at baseline, which is actually a good thing. And then she has another gene, the MAO gene. It also breaks down dopamine. And that one was also working very slow.

It plays a big role, although there are other parts of the brain, newer transmitters that do that as well. In her case, her gene breaks down dopamine very slowly. So she's predisposed to having a high level of dopamine in her brain at baseline, which is actually a good thing. And then she has another gene, the MAO gene. It also breaks down dopamine. And that one was also working very slow.

The role of those when those are really high, actually at baseline, your superpower will be the ability to focus and hyper-focus. The problem is that those two are also involved in the stress response. And people with a CMT, what we call met-met or slow-active, slow-performer, They tend to be anxious. They tend more towards depression. And they tend towards having ADHD.

The role of those when those are really high, actually at baseline, your superpower will be the ability to focus and hyper-focus. The problem is that those two are also involved in the stress response. And people with a CMT, what we call met-met or slow-active, slow-performer, They tend to be anxious. They tend more towards depression. And they tend towards having ADHD.

The role of those when those are really high, actually at baseline, your superpower will be the ability to focus and hyper-focus. The problem is that those two are also involved in the stress response. And people with a CMT, what we call met-met or slow-active, slow-performer, They tend to be anxious. They tend more towards depression. And they tend towards having ADHD.

Homozygous PT is slow. So she's met-met. Met-met is slow. That's met-met is, yeah, met-met and AA are the same. And that's slow. And she's going to build up her dopamine. So I found that she had the slow form of the CMT gene. Dopamine, we think, is great to be at higher levels in the prefrontal cortex. And it is. But it's also part of the fight or flight process.

Homozygous PT is slow. So she's met-met. Met-met is slow. That's met-met is, yeah, met-met and AA are the same. And that's slow. And she's going to build up her dopamine. So I found that she had the slow form of the CMT gene. Dopamine, we think, is great to be at higher levels in the prefrontal cortex. And it is. But it's also part of the fight or flight process.

Homozygous PT is slow. So she's met-met. Met-met is slow. That's met-met is, yeah, met-met and AA are the same. And that's slow. And she's going to build up her dopamine. So I found that she had the slow form of the CMT gene. Dopamine, we think, is great to be at higher levels in the prefrontal cortex. And it is. But it's also part of the fight or flight process.

reflex and dopamine in particular patients like claire her dopamine receptors also were impacted and so the dopamine when she's in her if everything's good she can concentrate but very little things would set her off she if if you know she'd have a phone call Somebody's going to be late, or she overdrew her bank account, or she failed a test. That would disrupt her very quickly.

reflex and dopamine in particular patients like claire her dopamine receptors also were impacted and so the dopamine when she's in her if everything's good she can concentrate but very little things would set her off she if if you know she'd have a phone call Somebody's going to be late, or she overdrew her bank account, or she failed a test. That would disrupt her very quickly.

reflex and dopamine in particular patients like claire her dopamine receptors also were impacted and so the dopamine when she's in her if everything's good she can concentrate but very little things would set her off she if if you know she'd have a phone call Somebody's going to be late, or she overdrew her bank account, or she failed a test. That would disrupt her very quickly.

She'd go into fight or flight because her dopamine levels and her norepinephrine levels are already high. They're very close to spilling over. So it doesn't take much to throw her into an anxiety state, in a state where she can't focus and concentrate. So we're able to balance that out. And there are ways of doing that.

She'd go into fight or flight because her dopamine levels and her norepinephrine levels are already high. They're very close to spilling over. So it doesn't take much to throw her into an anxiety state, in a state where she can't focus and concentrate. So we're able to balance that out. And there are ways of doing that.

She'd go into fight or flight because her dopamine levels and her norepinephrine levels are already high. They're very close to spilling over. So it doesn't take much to throw her into an anxiety state, in a state where she can't focus and concentrate. So we're able to balance that out. And there are ways of doing that.