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Dr. Glen D’Souza

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118 total appearances
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Appearances Over Time

Podcast Appearances

Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

So I think it's happening everywhere.

728.291 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

We see these systems in wastewater treatment plants, for instance.

729.993 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

We see that in agricultural context in the ocean.

733.899 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

It's funny, we found a lot of signatures of warfare, microbial warfare, about 6,000 feet on the ocean floor, right?

737.384 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

And it makes more sense there, right?

745.86 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

Because the nutrients there are extremely, extremely difficult to get.

748.305 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

Oxygen is a problem.

751.551 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

So yeah, so it's everywhere, except it might be at different levels in different places.

752.894 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

Yeah, I mean, definitely we can, right?

843.275 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

So one of these systems, as I keep on saying, is a spear gun, right?

845.338 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

What the spear gun does is delivers toxins into another cell.

848.822 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

But we can, you know, essentially these are assassins.

852.987 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

What if you train an assassin or what if you train a hitman to find or remove things you don't like, right?

856.992 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

For instance, historically, we've used antibiotics to get rid of undesirable bugs from our systems, except antibiotics are indiscriminate.

862.679 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

They might just kill everyone.

870.509 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

They might kill the good ones, right?

871.57 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

We know that these killing bacteria are extremely specific in who they like to target or what kind of bugs they like to target, at least in many cases.

872.772 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

What if we can learn more of this system and then engineer living antibiotics?

882.593 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

Essentially, you can load any drug on these killing systems and then...

887.523 View full episode →
Science Friday
Swords, cannibalism, poison: inside the world of killer microbes

create an assassin cell that you introduce in your microbiome and say, okay, go and find the undesirable one and displace it off, right?

892.955 View full episode →