Dr. Jeff Bland

And what we did is we took a group – this is our little research center we had in Gig Harbor, Washington at the time. We studied – I think it was 80 people that we had – 30 of those people were on a kind of a standard of care. And then 50 of them were on an intervention program, like you've just described.

And what we did is we took a group – this is our little research center we had in Gig Harbor, Washington at the time. We studied – I think it was 80 people that we had – 30 of those people were on a kind of a standard of care. And then 50 of them were on an intervention program, like you've just described.

And what we did is we took a group – this is our little research center we had in Gig Harbor, Washington at the time. We studied – I think it was 80 people that we had – 30 of those people were on a kind of a standard of care. And then 50 of them were on an intervention program, like you've just described.

This kind of dietary program that was high in phytochemicals, but was low in allergic substances, was free of gluten, didn't have sugar. Dairy, yeah. Yeah, all those kind of things. And we followed them. And we were the first group, I think, ever to look at liver detoxification. Look at gut integrity using lactulose mannitol test to measure gut permeability. How to measure leaky gut. Exactly.

This kind of dietary program that was high in phytochemicals, but was low in allergic substances, was free of gluten, didn't have sugar. Dairy, yeah. Yeah, all those kind of things. And we followed them. And we were the first group, I think, ever to look at liver detoxification. Look at gut integrity using lactulose mannitol test to measure gut permeability. How to measure leaky gut. Exactly.

This kind of dietary program that was high in phytochemicals, but was low in allergic substances, was free of gluten, didn't have sugar. Dairy, yeah. Yeah, all those kind of things. And we followed them. And we were the first group, I think, ever to look at liver detoxification. Look at gut integrity using lactulose mannitol test to measure gut permeability. How to measure leaky gut. Exactly.

And we looked at caffeine clearance. We looked at benzoate excretion for liver phase one and phase two detoxifications and clinical symptoms over the course of, I think it was two months. Yeah. And we saw about a 60% reduction in symptoms of the treatment group versus the control group. And that was published in 1991. That was a foundational statement starting functional medicine at that point.

And we looked at caffeine clearance. We looked at benzoate excretion for liver phase one and phase two detoxifications and clinical symptoms over the course of, I think it was two months. Yeah. And we saw about a 60% reduction in symptoms of the treatment group versus the control group. And that was published in 1991. That was a foundational statement starting functional medicine at that point.

And we looked at caffeine clearance. We looked at benzoate excretion for liver phase one and phase two detoxifications and clinical symptoms over the course of, I think it was two months. Yeah. And we saw about a 60% reduction in symptoms of the treatment group versus the control group. And that was published in 1991. That was a foundational statement starting functional medicine at that point.

You have taken that and moved it to a much higher state of refinement. But I'm very, very... proud to say that what we were starting to understand, and I want to emphasize starting, that the gut was connected to the immune system. The immune system was connected to the liver. The liver has its own immune system. 10% of the liver is occupied by what are called Kupfer cells that are immune cells.

You have taken that and moved it to a much higher state of refinement. But I'm very, very... proud to say that what we were starting to understand, and I want to emphasize starting, that the gut was connected to the immune system. The immune system was connected to the liver. The liver has its own immune system. 10% of the liver is occupied by what are called Kupfer cells that are immune cells.

You have taken that and moved it to a much higher state of refinement. But I'm very, very... proud to say that what we were starting to understand, and I want to emphasize starting, that the gut was connected to the immune system. The immune system was connected to the liver. The liver has its own immune system. 10% of the liver is occupied by what are called Kupfer cells that are immune cells.

Those cells then speak to the brain through systemic circulation of messenger substances All these things were started to be developed out of that early 1990s recognition that this is a system that patterns the control that ultimately is seen in people with different ranges of symptoms of different duration, variety, and intensity.

Those cells then speak to the brain through systemic circulation of messenger substances All these things were started to be developed out of that early 1990s recognition that this is a system that patterns the control that ultimately is seen in people with different ranges of symptoms of different duration, variety, and intensity.

Those cells then speak to the brain through systemic circulation of messenger substances All these things were started to be developed out of that early 1990s recognition that this is a system that patterns the control that ultimately is seen in people with different ranges of symptoms of different duration, variety, and intensity.

And so we were setting the tone, I believe, in that early study for what later became the architecture for functional medicine as a systems biology approach towards healthcare.

And so we were setting the tone, I believe, in that early study for what later became the architecture for functional medicine as a systems biology approach towards healthcare.

And so we were setting the tone, I believe, in that early study for what later became the architecture for functional medicine as a systems biology approach towards healthcare.

There are three things that we collaboratively developed that have now stuck as clinical tools that I think are important to acknowledge as we move into this immune question. So let's just review quickly. I want to review quickly what really we have collaboratively developed as clinical therapeutic tools. Number one is gut restoration. We originally call it the four-hour program.

There are three things that we collaboratively developed that have now stuck as clinical tools that I think are important to acknowledge as we move into this immune question. So let's just review quickly. I want to review quickly what really we have collaboratively developed as clinical therapeutic tools. Number one is gut restoration. We originally call it the four-hour program.