Dr. Jen Gunter

And then you can see, okay, you go on the other one, your symptoms are all still there, maybe it's not estrogen.

And what we can see is people push doses higher and higher and higher.

Well, if you have a uterus, we don't know how much progestogen I need to give you to protect your uterus with these super high levels.

And sometimes people are on like birth control pill doses even higher.

And we know that with age, we start to get more concerned about the higher doses.

Remember, all of the safety data is not with those doses, right?

So you have that issue, but also people can develop tachyflaxis.

And so they have awful symptoms.

They think those symptoms need to be treated with estrogen.

They go on more estrogen, they get more symptoms and it gets higher and higher and higher.

And we're seeing more of that.

That used to be like unheard of.

And I think that chasing levels is a big way that that's doing that.

Basically, if you're on a patch or you're on a cream or you're on a lotion, and this is all pharma hormones because compounds a whole different story.

and it's not reducing your hot flashes, it's not reducing your night sweats, then change to a different delivery mechanism as long as that mechanism is safe for you, or switch to a different estrogen.

So we have Premarin as opposed to Estradiol.

So you can make a logical switch and say, let's see.

But however, if your symptoms are something that we know is not well treated, so for example, when women have had their last period and they're in menopause,

estrogen doesn't seem to do anything for depression.

I mean, it makes you sleep better maybe, but it doesn't seem to affect that.