Dr Jessie Jacobson

So there's lots of research groups that have been working on this, and we know there's about 100 different genes that we know for sure if you have certain changes in them, they might underlie autism.

But we're also still discovering more and more all the time because it's complex.

It's really different from something like Huntington's, for instance, which we know it's one gene involved and one variant in that gene.

So it's a bit of both.

It's kind of exciting when you discover new things.

So autism itself, we know about 80% of it, the differences in autism can be explained by genetics.

It is, however, complex.

So sometimes there's a single gene involved for a family.

Likely in some families, there'll be combinations of different genes and variants in those genes that can contribute to autism.

So the genetics itself is quite complex.

We find an answer in about 30% of our cohort, which is very similar to international studies.

Some of that will be because, you know, for those families we don't will be, we're still understanding what genes are involved.

We're still understanding the types of variations in DNA that can contribute to autism.

We're still trying to figure out how we detect those.

And some of them will be more complex to tease apart, like the combinations of common variants.

So there's a lot of reasons why we're still taking a while to get a higher percentage.

But I think, yeah, that 30% is pretty good.

That's very good, I think.

You know, this is part of the amazing thing about autism is that, you know, it's so diverse.

The genetics are so diverse.