Dr. Jocelyn Wittstein

And if we can, that's what we're studying.

We want to know, because this isn't clearly answered.

We want to know, is hormone therapy that may include estradiol, testosterone, progesterone, are these things...

protective of the cartilage, especially in women, so that we can narrow that gap, that 35% difference in knee arthritis.

If we do end up showing that the resiliency or that ability of the cartilage to rebound is restored or maintained or related to the estradiol and progesterone levels,

you know, that may be another indication or it may expand our thoughts about like, what is hormone therapy for?

But we haven't clearly shown, and a lot of the old research, again, is on like different forms of hormone therapy.

Yeah.

Related to arthritis, though, it's kind of,

It's not necessarily looking at the actual health of the cartilage.

And so we're, yeah, so that we've submitted another grant to the NIH.

I just applied to another private foundation.

And yeah, so if anyone wants to help me solve arthritis and women call me, you can come to our lab.

I can show you how we do everything.

And I really, really hope we get funding for this because that is one of the studies I'm extremely excited about.

Yes.

One of the reasons why I like the EFOPS trial is, you know, we have all these studies that show, OK, jumping helps with hip bone density.

Strength training helps, you know, improve especially lumbar spine bone density.

Again, what we really want to prevent, like, yes, maintaining bone density is great and nice.

And we presume in most cases, like we know from many medications, you know, that improving bone density reduces fracture risk.