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Dr. John Kruse

👤 Person
915 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But more people with ADHD tend to, either because the drug is wearing off at the end of the day and there's some crash in alertness or energy, or because they're being more productively expending energy and are more tired at the end of the day, or it's just helping synchronize circadian clocks by getting a consistent start early in the day. We don't know the mechanism by which it works.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But more people with ADHD tend to, either because the drug is wearing off at the end of the day and there's some crash in alertness or energy, or because they're being more productively expending energy and are more tired at the end of the day, or it's just helping synchronize circadian clocks by getting a consistent start early in the day. We don't know the mechanism by which it works.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

But more people with ADHD tend to, either because the drug is wearing off at the end of the day and there's some crash in alertness or energy, or because they're being more productively expending energy and are more tired at the end of the day, or it's just helping synchronize circadian clocks by getting a consistent start early in the day. We don't know the mechanism by which it works.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's lots of plausible and overlapping ones, but Again, daytime alertness medications can help.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's lots of plausible and overlapping ones, but Again, daytime alertness medications can help.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's lots of plausible and overlapping ones, but Again, daytime alertness medications can help.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I was going to say, both of those have some science background, so I'd say I'm glad it works. And what's hard to sorting out is why it's working is one is, you know, potential placebo effect. You're doing it because you're thinking or hoping it works. Good. And two, I'd say maybe even more importantly than the placebo effect is the days that you're deciding to do this

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I was going to say, both of those have some science background, so I'd say I'm glad it works. And what's hard to sorting out is why it's working is one is, you know, potential placebo effect. You're doing it because you're thinking or hoping it works. Good. And two, I'd say maybe even more importantly than the placebo effect is the days that you're deciding to do this

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I was going to say, both of those have some science background, so I'd say I'm glad it works. And what's hard to sorting out is why it's working is one is, you know, potential placebo effect. You're doing it because you're thinking or hoping it works. Good. And two, I'd say maybe even more importantly than the placebo effect is the days that you're deciding to do this

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's something different about those days to begin with because they're not doing it every day. So those potential issues aside, I'll jump into insomnia. And Matthew Walker talks about some of this. To me, maybe the biggest finding in insomnia sleep medicine in the last 20 years is that almost everyone who has a problem with insomnia doesn't have a problem with sleep. Huh? What?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's something different about those days to begin with because they're not doing it every day. So those potential issues aside, I'll jump into insomnia. And Matthew Walker talks about some of this. To me, maybe the biggest finding in insomnia sleep medicine in the last 20 years is that almost everyone who has a problem with insomnia doesn't have a problem with sleep. Huh? What?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

There's something different about those days to begin with because they're not doing it every day. So those potential issues aside, I'll jump into insomnia. And Matthew Walker talks about some of this. To me, maybe the biggest finding in insomnia sleep medicine in the last 20 years is that almost everyone who has a problem with insomnia doesn't have a problem with sleep. Huh? What?

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That sounds like I'm contradicting myself. What I mean is the sleep system's intact, it's there, it's waiting to arrive and put you to sleep each night. What the problem, and this is from the sleep researchers, with at least 90% or probably more of people who have insomnia problems, is the failure of the daytime arousal system to shut off properly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That sounds like I'm contradicting myself. What I mean is the sleep system's intact, it's there, it's waiting to arrive and put you to sleep each night. What the problem, and this is from the sleep researchers, with at least 90% or probably more of people who have insomnia problems, is the failure of the daytime arousal system to shut off properly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

That sounds like I'm contradicting myself. What I mean is the sleep system's intact, it's there, it's waiting to arrive and put you to sleep each night. What the problem, and this is from the sleep researchers, with at least 90% or probably more of people who have insomnia problems, is the failure of the daytime arousal system to shut off properly.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So normally we have these two mutually inhibitory systems, wakefulness... arousal system and a sleep sedation system. And usually when one turns on, the other turns off. And with most people's problem with insomnia, it isn't that sleep is weak or insufficient or not there. It's sitting, it's waiting there. It just can't land on the landing pad because you're too aroused or too awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So normally we have these two mutually inhibitory systems, wakefulness... arousal system and a sleep sedation system. And usually when one turns on, the other turns off. And with most people's problem with insomnia, it isn't that sleep is weak or insufficient or not there. It's sitting, it's waiting there. It just can't land on the landing pad because you're too aroused or too awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

So normally we have these two mutually inhibitory systems, wakefulness... arousal system and a sleep sedation system. And usually when one turns on, the other turns off. And with most people's problem with insomnia, it isn't that sleep is weak or insufficient or not there. It's sitting, it's waiting there. It just can't land on the landing pad because you're too aroused or too awake.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I mean, maybe that helps the arousal system to turn off better at the end of the day if it's gotten more fully engaged during the day. I don't know. But it feeds back more into some of the non-medication approaches to helping with sleep, and that is doing everything you can, again, not just to force sleep or push it because that doesn't work very well. It's getting rid of arousal.

Huberman Lab
Improve Focus with Behavioral Tools & Medication for ADHD | Dr. John Kruse

I mean, maybe that helps the arousal system to turn off better at the end of the day if it's gotten more fully engaged during the day. I don't know. But it feeds back more into some of the non-medication approaches to helping with sleep, and that is doing everything you can, again, not just to force sleep or push it because that doesn't work very well. It's getting rid of arousal.