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Dr. Kevin Tracey

๐Ÿ‘ค Speaker
536 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Vagus Nerve Stimulation and the Immune System

Your heart rate goes up.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Your blood pressure goes up.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And that's the opposite, allegedly, of a parasympathetic arrest and digest response.

Ground Truths
Vagus Nerve Stimulation and the Immune System

But what happens if you stay in the cold water and you cold adapt?

Ground Truths
Vagus Nerve Stimulation and the Immune System

And here, Eric, it's very hard to find well-controlled...

Ground Truths
Vagus Nerve Stimulation and the Immune System

Clinical studies.

Ground Truths
Vagus Nerve Stimulation and the Immune System

I found a few, and they're in the book.

Ground Truths
Vagus Nerve Stimulation and the Immune System

But it's very hard.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Usually it's military-type soldiers in Iceland or something or in the Baltic states getting sprayed with water in a cold room and dressed in a bathing suit.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And then they give their blood.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So there's some data like this.

Ground Truths
Vagus Nerve Stimulation and the Immune System

If you cold adapt to some point for some period of time, you will actually feel your heart rate slow down, at which point you can say, my vagus response is exceeding my fight or flight response.

Ground Truths
Vagus Nerve Stimulation and the Immune System

They're both still active, by the way.

Ground Truths
Vagus Nerve Stimulation and the Immune System

But let's just say that you've tipped from primarily sympathetic to primarily parasympathetic.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So, okay, now you've stimulated your vagus nerve, but you've done a million other things to your nervous system

Ground Truths
Vagus Nerve Stimulation and the Immune System

Two, you haven't put a device on your neck targeting a few hundred fibers to turn off inflammation.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Now, do the fibers that made your blood pressure go up first and then down and your heart rate go up first and then go down, are those the same fibers that go to your spleen and control inflammation?

Ground Truths
Vagus Nerve Stimulation and the Immune System

I don't think so.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Does the whole thing act as an on-block effect?

Ground Truths
Vagus Nerve Stimulation and the Immune System

everything at once response?