Dr. Layne Norton

I don't know the answer.

But I would suspect based on other things I've seen that it's probably going to be really no difference, that it is a tool to control calories and that's what affects autophagy.

On longevity, I mean really there's some animal studies.

There's some in vitro stuff as well.

I think –

And even the calorie restriction stuff, I think I have kind of a unique take on this because I've done animal research.

So there's nothing I'm aware – I mean there's a couple of rodent studies looking at time-restricted eating where they suggested a longevity benefit.

I think rodent model is probably a poor model for longevity because rodents grow throughout the course of their life.

Humans kind of peak at like around 20 and then they kind of stay level, I mean obesity notwithstanding, and then they start to decline later in life.

Very different growth curve from rodents.

Now, rodents are good models for other things like protein metabolism, decent model for glucose metabolism.

But for longevity, I'm not convinced.

Now, if we look at the monkey studies, the primate studies, we see the calorie restriction effects on primates, right?

And so I think, but I'm not even convinced it's calorie restriction.

And here's why.

Because I know how these studies are done.

because when you're looking at lab animals, you just look at what they normally eat and then you cut 20, 30% out and you go, that's calorie restriction.

But I pulled up these studies and looked at the, and looked at the charts of these animals' weights.

They don't like keep dropping.

There's like maybe a little drop and then it just kind of plateaus, right?