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Dr. Layne Norton

👤 Person
4445 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so what that says, and then no difference in BMR. And then actually people who eat more cruciferous vegetables actually tend to be a little bit leaner, but that could be a little bit healthy user bias. And they'd probably just eat less calories because they're more satiated, but it's certainly not going the opposite direction. Right. And so,

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so what that says, and then no difference in BMR. And then actually people who eat more cruciferous vegetables actually tend to be a little bit leaner, but that could be a little bit healthy user bias. And they'd probably just eat less calories because they're more satiated, but it's certainly not going the opposite direction. Right. And so,

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so what that says, and then no difference in BMR. And then actually people who eat more cruciferous vegetables actually tend to be a little bit leaner, but that could be a little bit healthy user bias. And they'd probably just eat less calories because they're more satiated, but it's certainly not going the opposite direction. Right. And so,

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

The point is, again, if an outcome exists, there is absolutely a mechanism to explain it. But just because a mechanism exists does not mean you're going to produce an outcome. And I got exposed to this very early because I cut my teeth on the bodybuilding message boards back in the day where it was a bunch of nerds arguing with each other, mostly who had no background arguing.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

The point is, again, if an outcome exists, there is absolutely a mechanism to explain it. But just because a mechanism exists does not mean you're going to produce an outcome. And I got exposed to this very early because I cut my teeth on the bodybuilding message boards back in the day where it was a bunch of nerds arguing with each other, mostly who had no background arguing.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

The point is, again, if an outcome exists, there is absolutely a mechanism to explain it. But just because a mechanism exists does not mean you're going to produce an outcome. And I got exposed to this very early because I cut my teeth on the bodybuilding message boards back in the day where it was a bunch of nerds arguing with each other, mostly who had no background arguing.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there were some actual like sports scientists and professors who would get on those every once in a while. This was before social media existed. And I remember I was in biochemistry class. This is 2003. And they're talking about how caffeine inhibits glycogen phosphorylase, which is a mechanism. And it exists. Caffeine inhibits glycogen phosphorylase.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there were some actual like sports scientists and professors who would get on those every once in a while. This was before social media existed. And I remember I was in biochemistry class. This is 2003. And they're talking about how caffeine inhibits glycogen phosphorylase, which is a mechanism. And it exists. Caffeine inhibits glycogen phosphorylase.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

But there were some actual like sports scientists and professors who would get on those every once in a while. This was before social media existed. And I remember I was in biochemistry class. This is 2003. And they're talking about how caffeine inhibits glycogen phosphorylase, which is a mechanism. And it exists. Caffeine inhibits glycogen phosphorylase.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so I made this post where I – on the forums and I said, well, we should be having caffeine after a workout then because it will help with glycogen resynthesis because it will keep glycogen phosphorylase from breaking down glycogen. And somebody came in and said, you're really like zooming in on a blade of grass instead of zooming out and looking at the forest, right?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so I made this post where I – on the forums and I said, well, we should be having caffeine after a workout then because it will help with glycogen resynthesis because it will keep glycogen phosphorylase from breaking down glycogen. And somebody came in and said, you're really like zooming in on a blade of grass instead of zooming out and looking at the forest, right?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And so I made this post where I – on the forums and I said, well, we should be having caffeine after a workout then because it will help with glycogen resynthesis because it will keep glycogen phosphorylase from breaking down glycogen. And somebody came in and said, you're really like zooming in on a blade of grass instead of zooming out and looking at the forest, right?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And biochemists – I was guilty of this and biochemists by trade, we get very focused on pathways. But if you think about what caffeine does overall, activates the sympathetic nervous system, its function is to, like, you're liberating fuel. And some people, when they take caffeine, actually have a rise in blood glucose. So that is the outcome.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And biochemists – I was guilty of this and biochemists by trade, we get very focused on pathways. But if you think about what caffeine does overall, activates the sympathetic nervous system, its function is to, like, you're liberating fuel. And some people, when they take caffeine, actually have a rise in blood glucose. So that is the outcome.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And biochemists – I was guilty of this and biochemists by trade, we get very focused on pathways. But if you think about what caffeine does overall, activates the sympathetic nervous system, its function is to, like, you're liberating fuel. And some people, when they take caffeine, actually have a rise in blood glucose. So that is the outcome.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

is actually counter to what that biochemical pathway is. And so we've got to be really careful with how we promote these biochemical pathways. I mean, I did a really funny post on Twitter where myself and Joseph Sundell, I'm not sure if you're familiar with him. He's a cancer biologist.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

is actually counter to what that biochemical pathway is. And so we've got to be really careful with how we promote these biochemical pathways. I mean, I did a really funny post on Twitter where myself and Joseph Sundell, I'm not sure if you're familiar with him. He's a cancer biologist.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

is actually counter to what that biochemical pathway is. And so we've got to be really careful with how we promote these biochemical pathways. I mean, I did a really funny post on Twitter where myself and Joseph Sundell, I'm not sure if you're familiar with him. He's a cancer biologist.

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And we were joking back and forth. I said, you know what? I bet I could like come up with a pathway to get people to eat poop. Like I can make a compelling argument for just eating poop. And then he goes, he's like, I'll take that bet. I'm like, okay, let's give it a shot. So I'm like, what is some of the most common compounds in human fecal matter?

Huberman Lab
Tools for Nutrition & Fitness | Dr. Layne Norton

And we were joking back and forth. I said, you know what? I bet I could like come up with a pathway to get people to eat poop. Like I can make a compelling argument for just eating poop. And then he goes, he's like, I'll take that bet. I'm like, okay, let's give it a shot. So I'm like, what is some of the most common compounds in human fecal matter?