Dr. Layne Norton

Favoring equal distribution, right? Now, again, hard to repeat that study in humans, right? And for the duration it's done. So I came out saying, you know what? That's actually less than I thought we were going to – I thought we were going to find bigger differences than that.

Because, I mean, if you're thinking about number of times you're stimulating protein synthesis, I mean one per day versus three per day, I mean shouldn't there be like a pretty significant difference there? And it was – I mean it reached the level of significance. But again, I thought the effect size was smaller than I thought. And so I kind of walked out saying, you know what?

Because, I mean, if you're thinking about number of times you're stimulating protein synthesis, I mean one per day versus three per day, I mean shouldn't there be like a pretty significant difference there? And it was – I mean it reached the level of significance. But again, I thought the effect size was smaller than I thought. And so I kind of walked out saying, you know what?

Because, I mean, if you're thinking about number of times you're stimulating protein synthesis, I mean one per day versus three per day, I mean shouldn't there be like a pretty significant difference there? And it was – I mean it reached the level of significance. But again, I thought the effect size was smaller than I thought. And so I kind of walked out saying, you know what?

Total protein intake is the most important thing per day. And then if you can distribute it relatively evenly, that's maybe the last 5% to 10%, right? And you've seen some human studies where it seems to matter. Most seem to show it doesn't really matter that much. Here's what I think. If you're measuring an outcome like lean mass, that doesn't change much in eight weeks, unfortunately.

Total protein intake is the most important thing per day. And then if you can distribute it relatively evenly, that's maybe the last 5% to 10%, right? And you've seen some human studies where it seems to matter. Most seem to show it doesn't really matter that much. Here's what I think. If you're measuring an outcome like lean mass, that doesn't change much in eight weeks, unfortunately.

Total protein intake is the most important thing per day. And then if you can distribute it relatively evenly, that's maybe the last 5% to 10%, right? And you've seen some human studies where it seems to matter. Most seem to show it doesn't really matter that much. Here's what I think. If you're measuring an outcome like lean mass, that doesn't change much in eight weeks, unfortunately.

It's very small differences. And so I think it's going to be hard to detect that. But what I'll tell people is if you're asking, can you build muscle intermittent fasting? Absolutely. Can you build a lot of muscle? Probably. If you are a bodybuilder, specific population, or if your goal is to be the most muscular, strongest human being you can possibly become,

It's very small differences. And so I think it's going to be hard to detect that. But what I'll tell people is if you're asking, can you build muscle intermittent fasting? Absolutely. Can you build a lot of muscle? Probably. If you are a bodybuilder, specific population, or if your goal is to be the most muscular, strongest human being you can possibly become,

It's very small differences. And so I think it's going to be hard to detect that. But what I'll tell people is if you're asking, can you build muscle intermittent fasting? Absolutely. Can you build a lot of muscle? Probably. If you are a bodybuilder, specific population, or if your goal is to be the most muscular, strongest human being you can possibly become,

I think you're probably better off not doing intermittent fasting just because those last that last five percent may make a big difference. And you're never going to be able to pick that out of a human randomized control trial in eight weeks. At least I don't think you will.

I think you're probably better off not doing intermittent fasting just because those last that last five percent may make a big difference. And you're never going to be able to pick that out of a human randomized control trial in eight weeks. At least I don't think you will.

I think you're probably better off not doing intermittent fasting just because those last that last five percent may make a big difference. And you're never going to be able to pick that out of a human randomized control trial in eight weeks. At least I don't think you will.

And so, again, I don't have any human data to really back that up, but just based on what I know about signaling and the effects we saw on animals, that's kind of my recommendation. But most people don't fall in that category. Most people are just worried about, hey, I want to look good, build a little bit of muscle. Intermittent fasting is a perfectly fine tool for doing that.

And so, again, I don't have any human data to really back that up, but just based on what I know about signaling and the effects we saw on animals, that's kind of my recommendation. But most people don't fall in that category. Most people are just worried about, hey, I want to look good, build a little bit of muscle. Intermittent fasting is a perfectly fine tool for doing that.

And so, again, I don't have any human data to really back that up, but just based on what I know about signaling and the effects we saw on animals, that's kind of my recommendation. But most people don't fall in that category. Most people are just worried about, hey, I want to look good, build a little bit of muscle. Intermittent fasting is a perfectly fine tool for doing that.

I will say, you know, obviously we haven't studied some of the more extreme forms of fasting in terms of building muscle, right? Like the 16-8 has been studied previously. But like I'm thinking of a study that was done without resistance training, alternate day fasting versus continuous kind of normal feeding.

I will say, you know, obviously we haven't studied some of the more extreme forms of fasting in terms of building muscle, right? Like the 16-8 has been studied previously. But like I'm thinking of a study that was done without resistance training, alternate day fasting versus continuous kind of normal feeding.

I will say, you know, obviously we haven't studied some of the more extreme forms of fasting in terms of building muscle, right? Like the 16-8 has been studied previously. But like I'm thinking of a study that was done without resistance training, alternate day fasting versus continuous kind of normal feeding.

Right. So they did.