Dr. Layne Norton

And so really like based on some of the chrononutrition stuff we've seen from some of the lesser well-controlled trials, they were expecting to see differences in like glucose metabolism and whatnot. And they just didn't really see a difference in anything. And the only – I think the only thing they saw a little bit of a difference was in fasting blood glucose. And here's what I tell people.

And so really like based on some of the chrononutrition stuff we've seen from some of the lesser well-controlled trials, they were expecting to see differences in like glucose metabolism and whatnot. And they just didn't really see a difference in anything. And the only – I think the only thing they saw a little bit of a difference was in fasting blood glucose. And here's what I tell people.

And so really like based on some of the chrononutrition stuff we've seen from some of the lesser well-controlled trials, they were expecting to see differences in like glucose metabolism and whatnot. And they just didn't really see a difference in anything. And the only – I think the only thing they saw a little bit of a difference was in fasting blood glucose. And here's what I tell people.

When you see a difference in fasting blood glucose but not HbA1c, you're looking at a transient difference. And what I mean by that is HbA1c is such a great measurement because it's an area on hemoglobin that can be glycosylated. And so that is very dependent on what is your overall concentration of glucose in the blood over a 24-hour period of time.

When you see a difference in fasting blood glucose but not HbA1c, you're looking at a transient difference. And what I mean by that is HbA1c is such a great measurement because it's an area on hemoglobin that can be glycosylated. And so that is very dependent on what is your overall concentration of glucose in the blood over a 24-hour period of time.

When you see a difference in fasting blood glucose but not HbA1c, you're looking at a transient difference. And what I mean by that is HbA1c is such a great measurement because it's an area on hemoglobin that can be glycosylated. And so that is very dependent on what is your overall concentration of glucose in the blood over a 24-hour period of time.

because it's exposed the entire time it's in your bloodstream. So whether you're getting glucose spikes at meals or you have higher fasting blood glucose, it's going to be very reflective of the overall 24-hour area under the curve, right? So why do some of these studies see a little bit better improvement in lowering fasting blood glucose, whereas HbA1c doesn't show up? Well, think about it.

because it's exposed the entire time it's in your bloodstream. So whether you're getting glucose spikes at meals or you have higher fasting blood glucose, it's going to be very reflective of the overall 24-hour area under the curve, right? So why do some of these studies see a little bit better improvement in lowering fasting blood glucose, whereas HbA1c doesn't show up? Well, think about it.

because it's exposed the entire time it's in your bloodstream. So whether you're getting glucose spikes at meals or you have higher fasting blood glucose, it's going to be very reflective of the overall 24-hour area under the curve, right? So why do some of these studies see a little bit better improvement in lowering fasting blood glucose, whereas HbA1c doesn't show up? Well, think about it.

If somebody has early time-restricted feeding and they finish most of their food intake before 1 p.m., They have an extra like six, seven, eight hours that they're not hardly eating anything. It doesn't surprise me that the next morning, because they've technically fasted for longer, you have a lower blood glucose. Now, I can't really back this up straight up because nobody's ever measured it.

If somebody has early time-restricted feeding and they finish most of their food intake before 1 p.m., They have an extra like six, seven, eight hours that they're not hardly eating anything. It doesn't surprise me that the next morning, because they've technically fasted for longer, you have a lower blood glucose. Now, I can't really back this up straight up because nobody's ever measured it.

If somebody has early time-restricted feeding and they finish most of their food intake before 1 p.m., They have an extra like six, seven, eight hours that they're not hardly eating anything. It doesn't surprise me that the next morning, because they've technically fasted for longer, you have a lower blood glucose. Now, I can't really back this up straight up because nobody's ever measured it.

But that, I think, is a logical explanation while you see some of this stuff. And that's why I tell people the measurement you take really matters. I think fasting blood glucose is a useful measurement. But I put much more value on something like HOMA-IR, euglycemic clamp, or – HBA1C. So anyways, I think the early versus late time restricted kind of doesn't matter too much.

But that, I think, is a logical explanation while you see some of this stuff. And that's why I tell people the measurement you take really matters. I think fasting blood glucose is a useful measurement. But I put much more value on something like HOMA-IR, euglycemic clamp, or – HBA1C. So anyways, I think the early versus late time restricted kind of doesn't matter too much.

But that, I think, is a logical explanation while you see some of this stuff. And that's why I tell people the measurement you take really matters. I think fasting blood glucose is a useful measurement. But I put much more value on something like HOMA-IR, euglycemic clamp, or – HBA1C. So anyways, I think the early versus late time restricted kind of doesn't matter too much.

So again, we're rubber meets the road in practicality versus what hardline research says. So I am not real convinced at all that it really matters when you eat your carbohydrate intake.

So again, we're rubber meets the road in practicality versus what hardline research says. So I am not real convinced at all that it really matters when you eat your carbohydrate intake.

So again, we're rubber meets the road in practicality versus what hardline research says. So I am not real convinced at all that it really matters when you eat your carbohydrate intake.

Because my bias has been validated, I can leave now. So I really try to get people focused on the stuff that matters the most, right? So this is, if we're worried about carbohydrate timing... Even if there are differences, we are zoomed way in on the blade of grass, right? We're not zooming out all the way.

Because my bias has been validated, I can leave now. So I really try to get people focused on the stuff that matters the most, right? So this is, if we're worried about carbohydrate timing... Even if there are differences, we are zoomed way in on the blade of grass, right? We're not zooming out all the way.