Dr. Luc (Luke) van Loon

Now, if you're in a gym and you want to take a certain amount of protein and you don't want to make a short meal and you want to restrict calories, yeah, then sometimes a protein shake is easy, easier.

Yeah.

so this is stuff that we the whole intrinsically labeled cows to the cow infusion getting intrinsically labeled milk and we extracted whey and casein in order to to show the digestion and absorption kinetics and also the capacity to stimulate muscle protein synthesis now we've done these studies years ago and that shows that micellar casein is a slowly digestible protein

So the increase in circulating essential amino acids in the blood is more sluggish than when you ingest whey protein, which is more rapidly digestible protein.

And so the whey protein gets or is more rapidly digested, greater increase in muscle protein synthesis.

and also has a greater anabolic response, greater increase in muscle protein synthesis.

Now we thought that's maybe only because of the more rapid digestion and absorption, so we hydrolyzed the casein, make it more rapidly digestible, so it was just as easily digested and absorbed as the whey, but it still had a lesser response.

So that might be due to the lesser amount of leucine

in case in the new way way has a higher Lucy content and we know that Lucy is a is an is a is a is an amino acids that has very strong signaling properties so it stimulates the entire pathway and therefore it sets off the whole anabolic cascade and

We also double-checked that by adding free leucine on the casein, and we got a greater response.

So in short, we know that the anabolic potential of a protein is related to the rate of digestion and absorption and the amount of, at least the amount of leucine in combination with other amino acids.

And that's the whole basis of why whey is more popular with athletes than casein.

But the differences are very small.

And so for practice in combination with diets and throughout the whole day, all the food that you eat, it's very minimal.

But of course, I mean, I ride a bike that is only nine kilos, but I might have actually 15 kilograms of overweight.

So I could actually do with a much heavier bike, but I still want the fastest bike and the lightest bike.

And so people want the best supplement.

Does it make that much of a difference?

I don't think so that much.

Sitting upright while you eat or actually chewing well has also a huge effect on the rate of digestion and absorption.