Dr. Luc (Luke) van Loon

We don't see it, at least not with the 20 grams or the 30 gram amounts.

Why would it work or why would it have an effect?

Because the suggestion is, and that's the story behind it, there's actually two stories.

One is that collagen has a lot of glycine and proline.

And of course, collagen is composed in your body, also a lot of glycine and proline, and maybe there's not a lot of those amino acids in our food, in our nutrition.

But of course, it doesn't matter that it actually increases muscle protein synthesis.

So now we've tried it now like three studies and so far we have not shown evidence that collagen increases connective tissue protein synthesis in muscle.

But yeah, I have to admit that the muscle fraction is only a very small amount of collagen.

So what about other tissues?

Cartilage, bone, tendons, ligaments, which is more than 80% collagen.

Maybe there it's more relevant.

And maybe even more relevant when you had surgery.

And you basically yourself, you have to reattach everything.

You have to renew all those collagen structures.

Maybe there it is a benefit.

Now, there's also people suggesting that in collagen, and especially hydrolyzed collagen, there's functional peptides that are bioactive, bioactive peptides.

So far, we haven't seen anything of that.

There's always discussions like, what are those peptides then?

Haven't seen any data to convince me yet.

And of course, it is not that the amino acids in collagen are not being used.