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Dr. Majid Fotuhi

šŸ‘¤ Speaker
1224 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

But Alzheimer's disease itself has mild, moderate, severe.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

And a border between MCI and early stage Alzheimer's disease is kind of gray area.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

Recent studies have shown

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

that if you provide people who have mild cognitive impairment or early stages of alzheimer's disease and you provide them with a multi-disciplinary program that combines the five pillars of brain health that you reverse that amyloid build up in the brain remember i mentioned earlier that there are two bagger things when it comes to

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

brain shrinkage with aging that eventually results in Alzheimer's disease.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

One bag is the plaques and tangles.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

It's had these proteins that clump together and when they come together to cause inflammation and brain shrinkage and a whole bag of things that are due to lifestyle related factors, poor sleep, sleep apnea, too much stress, poor diet and all those things.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

Now, usually people only look at the plaques and tangles as a marker of Alzheimer's disease, even though these other factors are equally, if not more important.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

What's exciting and is thrilling is that

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

The multimodal lifestyle interventions have been shown to reduce the amount of flax and tangles in the brain.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

The amyloid and tau levels drop with these lifestyle interventions.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

One study was done here in California.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

Dr. Ornish did the program where he provided a randomized controlled trial

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

in which one arm patients who had myocardial impairment or early stages of Alzheimer's disease received brain training, diet, socialization, exercise.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

And the other group was told to wait, we're gonna provide this program for you in six months.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

And then they monitored them and they had obtained levels of amyloid in the blood as a marker of how much amyloid in the brain at the beginning and at the end.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

And guess what?

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

the amyloid levels dropped in these patients.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

There are many other similar studies ongoing now to replicate this study.

Dhru Purohit Show
Alzheimer’s Isn’t Inevitable: The Science of Building a Stronger, Healthier Brain at Any Age with Dr. Majid Fotuhi

There are also new drugs that have reduced amyloid levels in the brain.