Dr. Majid Fotuhi

And I actually published a study in 1997 where we looked at individuals with low versus high omega-3 fatty acids and their incidence of Alzheimer's.

And we found that people who had high levels of omega-3

were less likely to get Alzheimer's disease, very similar to the Biobank data you just mentioned.

One interesting study is in France to look at incidents of Alzheimer's disease and omega-3 index in towns near the ocean versus town center of France.

And they found that people who live near the water and eat fish more often had higher levels of omega-3 fatty acid and they had lower incidence of Alzheimer's disease.

Yes, and also there is the vegetarian version of omega 3 fatty acids from algae.

Algae, right.

So there's a form called algal DHA that is for people who are vegetarian.

Mindset.

We just talked about stress and the effects of stress in the brain.

When you stress out, you increase levels of cortisol, and cortisol is like a poison for hippocampus.

When you increase cortisol levels, hippocampus shrinks more so than other parts of the brain.

And there are literally a dozen studies that have shown in humans that when you have high cortisol levels, your hippocampus is smaller.

One study in Japan looked at people in their sixties and they did baseline cortisol levels and did the baseline MRI.

And then they looked at them seven years later to see what happens to people with different level of baseline, cortisol level, baseline stress.

baseline high stress and high cortisol level versus those who have low stress and low cortisol levels.

And then seven years later, they saw that people who had high cortisol levels, they had as much small hippocampus than people who had low cortisol levels.

And lots of other studies have shown that if you just bring, let's say 200 people and do a questionnaire about the stress level and do a blood test for cortisol and just do MRI, those with higher cortisol levels have a small hippocampus.

That is well established.

Now, mindset is one thing is to manage your stress.