Dr. Mark Hyman

And the answer is that nature is super intelligent. Because it is recognized that regulatory function of genes requires multiple cell-specific activities to orchestrate outcome for maximum resilience, to maintain the redundancy of our system so that we have maximum opportunities for positive outcome from exposure. Now, why do those flavonoids get built in the plant? It wasn't for us, obviously.

It was because that's the plant's immune system. And that plant is subjected to really hostile conditions. Yeah, the climate is horrible. The soil is horrible. The insects are there, the mold and rust and all this stuff. So it has, plus it gets sunburned like mad.

It was because that's the plant's immune system. And that plant is subjected to really hostile conditions. Yeah, the climate is horrible. The soil is horrible. The insects are there, the mold and rust and all this stuff. So it has, plus it gets sunburned like mad.

It was because that's the plant's immune system. And that plant is subjected to really hostile conditions. Yeah, the climate is horrible. The soil is horrible. The insects are there, the mold and rust and all this stuff. So it has, plus it gets sunburned like mad.

So it has all these members of its orchestra that are there to play this suite of immune innate function that allows it to survive for millions, well, hundreds of thousands, probably millions of years.

So it has all these members of its orchestra that are there to play this suite of immune innate function that allows it to survive for millions, well, hundreds of thousands, probably millions of years.

So it has all these members of its orchestra that are there to play this suite of immune innate function that allows it to survive for millions, well, hundreds of thousands, probably millions of years.

And it turns out, lo and behold, that the mechanism by which that plant is able to protect itself by these compounds speaks right into the mechanism that our innate immune system in humans when consuming that plant can use as fuel, can use as information. So here's a specific example of food as information. It's not just an antioxidant effect.

And it turns out, lo and behold, that the mechanism by which that plant is able to protect itself by these compounds speaks right into the mechanism that our innate immune system in humans when consuming that plant can use as fuel, can use as information. So here's a specific example of food as information. It's not just an antioxidant effect.

And it turns out, lo and behold, that the mechanism by which that plant is able to protect itself by these compounds speaks right into the mechanism that our innate immune system in humans when consuming that plant can use as fuel, can use as information. So here's a specific example of food as information. It's not just an antioxidant effect.

It's a gene expression effect through this epigenetic regulation of multiple genes that are controlling multiple functions. So now let's go to your question, which is what about this research trial that we did? So in this case, we asked in humans, without controlling their diet. Just go ahead and eat your normal ad-lib diet, so it's not going to be a diet-controlled study.

It's a gene expression effect through this epigenetic regulation of multiple genes that are controlling multiple functions. So now let's go to your question, which is what about this research trial that we did? So in this case, we asked in humans, without controlling their diet. Just go ahead and eat your normal ad-lib diet, so it's not going to be a diet-controlled study.

It's a gene expression effect through this epigenetic regulation of multiple genes that are controlling multiple functions. So now let's go to your question, which is what about this research trial that we did? So in this case, we asked in humans, without controlling their diet. Just go ahead and eat your normal ad-lib diet, so it's not going to be a diet-controlled study.

What happens if we gave you a fairly enriched level of these Himalayan tartary buckwheat polyphenols, this array of substances, to the level that you were going to get about 1,200 milligrams a day? That would be equivalent to consuming about a half a cup of tartary buckwheat flour a day. It would be equivalent to that.

What happens if we gave you a fairly enriched level of these Himalayan tartary buckwheat polyphenols, this array of substances, to the level that you were going to get about 1,200 milligrams a day? That would be equivalent to consuming about a half a cup of tartary buckwheat flour a day. It would be equivalent to that.

What happens if we gave you a fairly enriched level of these Himalayan tartary buckwheat polyphenols, this array of substances, to the level that you were going to get about 1,200 milligrams a day? That would be equivalent to consuming about a half a cup of tartary buckwheat flour a day. It would be equivalent to that.

And the reason we chose that is that there were data that had already been published in the Asian medical literature showing that they could show clinical effects in humans in terms of improved insulin sensitivity, reduced inflammation, reduced lipids when they fed that amount of flour to individuals. So I said, okay, let's study it at the gene level in immune cells.

And the reason we chose that is that there were data that had already been published in the Asian medical literature showing that they could show clinical effects in humans in terms of improved insulin sensitivity, reduced inflammation, reduced lipids when they fed that amount of flour to individuals. So I said, okay, let's study it at the gene level in immune cells.

And the reason we chose that is that there were data that had already been published in the Asian medical literature showing that they could show clinical effects in humans in terms of improved insulin sensitivity, reduced inflammation, reduced lipids when they fed that amount of flour to individuals. So I said, okay, let's study it at the gene level in immune cells.

And lo and behold, in these individuals, when they consumed that level of these polyphenols over the course of 90 days, so three months, what did we find? Now, we were told when we started this study, we probably wouldn't find anything of statistical significance because the background of diet would overcome whatever signal we're getting from the supplement.