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Dr. Martin Picard

๐Ÿ‘ค Speaker
1629 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then those mitochondria, there's a single type of mitochondria in there.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then when it's fertilized, development happens in this beautiful process.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And through that process, as the heart starts to form, the brain starts to form, the muscles start to form, the mitochondria differentiate.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then you end up with different types of mitochondria that are adapted and matched to the different demands of cell types, of organs.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And one way we think about this is I think it's

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

it makes a lot of sense to think about mitochondria as social organisms.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And there are multiple features of mitochondrial biology that obey what behavioral social scientists classify as social.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

If you study ants, for example, there's a few rules that we know ants are social creatures because they form groups and there are different types.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

There's division of labor.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

You have worker ants that work really hard, and you have warrior ants that are really chubby, and they're here to defend the hive.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

They like to fight.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Yeah, exactly.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So those two types of ants, you look at them side by side, there's this little flimsy, super active worker ant, and then this chubby warrior ant.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Genetically, they're identical.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

They have the same genome.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

They came as a little larvae from the queen, but their morphology is super different.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Their behavior is very different, but through development, their cues are different.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

apply it to the different larvae, and then they end up becoming a worker or a worrier.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So the same kind of thing happens in mitochondria.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So there are different types of mitochondria, like the two types of ants.