Dr. Martin Picard

Then around like 70 years old, you start to see this decline.

Bringing oxygen to your mitochondria.

Yeah.

It depends at what level you look at metabolism.

If you look at the cellular level, they're- I'm referring to the basal caloric need.

We've developed a model called the energy conservation model, the brain-body energy conservation model of aging, the BEC model.

And so we could dive into this.

But I think there's significant changes that happen in some cells.

As cells age, they start to actually burn energy faster.

When cells become senescent, they burn energy faster.

And then they're sending signals.

I'm struggling, energetically speaking.

And that's what I think inflammation is.

You have some cells, not all cells, some cells in the body, they're kind of over the edge, they're becoming senescent, and then they send signals.

And those signals are the same signal that we release during sickness behavior.

If your immune system is like really struggling energetically because it's trying to fight off a virus, it's gonna send those same cytokines.

And when those cytokines reach the brain, the brain says, oh shit.

We're going to go bankrupt.

You know, the energy budget is threatened here.

So let's save energy.