Dr. Martin Picard

Lose your vitality, your vigor, at least for a little bit.

Yep.

And rest.

And like Arnold said, you become stronger, you make your mitochondria, more mitochondria, and you become fitter, not during the exercise, it's during the rest period.

So getting sleep, six to eight hours, definitely.

And about stimulants, like caffeine.

and other stimulants, what they do is they prevent you from feeling energetic stress.

So if energy is not flowing properly in your body and you should be sleeping to kind of decrease that energy resistance, then those stimulants kind of make you oblivious to those signals.

And now there are clinical trials, which I think are potentially dangerous, that are happening where –

Those drugs are being developed, antibody-based drugs, to prevent the brain from feeling signals of energetic stress in the body.

Well, if you think about it simplistically, and you think the body is a molecular machine, you think, here's what's happening when people are sick to have cancer.

Right?

GDF-15, just growth differentiation factor 15, which is a protein.

It's a cytokine.

It's secreted by cells when energy can't flow properly in mitochondria.

So if the cell is burning energy faster than it can sustain, it will start to secrete GDF-15.

So people with cancer who end up developing cachexia, right?

Their muscles...

melt away, they tend to have very high GDF-15.

And then GDF-15 can go to the brain.