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Dr. Martin Picard

πŸ‘€ Speaker
1629 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then...

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

The thinking, I think our way of thinking energetically about GDF-15 is a little different than what the rest of, I think, the field thinks.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

People see GDF-15 as a marker of inflammation.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then maybe that's like immune.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

I think it's a marker of energetic stress.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

The heart is calling out for help and trying to kind of

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

calm down the rest of the system, right?

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And by signaling onto the brain.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Turns out many more people developed heart failure and like adverse events under the drug.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So they stopped the trial.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Where you block GD15.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Yes.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

There's a lot of beautiful things.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Likely both are true, yes.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Okay.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And I think what we discovered is that hair graying, at least temporarily, is reversible.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And this was surprising because it goes against this notion that aging is a linear process that just happens over time no matter what you do.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And here we should know, actually, a hallmark of aging, which is depigmentation, losing color in your beard and your hair.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

It's something that happens to almost everyone, but at different stages of life and so on.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then on the same person, and the reason we got into this was that this felt like the perfect experiment.