Dr. Mary Claire Haver

So the mood data is actually really interesting.

Almost all of the studies looking at mood and testosterone actually favor testosterone, but all of the, quote, confidence intervals cross one, which means that they are not statistically significant.

But it's different than like cognition where you see it kind of all over the place.

The mood ones actually consistently trend towards a benefit.

But again, if you are looking at could this be due to chance?

Absolutely.

And could it be due to the placebo effect?

Absolutely.

Things like mood are incredibly affected by the placebo effect.

Right.

And if we talk about the story of libido...

and testosterone, I've got a great story about how the placebo effect is the entire reason that we don't have an FDA approved product for women.

It's because of that placebo effect.

Do you want to hear that story?

Yes.

Okay.

So in the early 2000s, there was a lot of data coming out looking at testosterone for low libido.

There was a patch, a 300 microgram patch that was studied.

It was brought to the FDA around 2007 for approval.

And the FDA said, we can see that it seems to improve libido, so sexual desire, as well as satisfying sexual events.