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Dr. Matthew B. (Matt) (likely the presenter) - Unknown

👤 Person
482 total appearances

Appearances Over Time

Podcast Appearances

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

It goes back into the muscle.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

It goes to the kidneys.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

It goes to the liver.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

And it's serving a very utilizable source of energy.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

So lactate can be used and converted into...

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

acetyl-CoA and used by energy, by the mitochondria.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

But probably one of its most important roles is as a signaling molecule.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

It's a way for your muscle to connect, to communicate with other organs and other tissues.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

And one of its signaling roles is back in the muscle, it's increasing the translocation of glucose-4 transporters to the cell surface of the muscles.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

glute four transporters.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

And so lactate gets back into the muscle.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

It's basically telling the muscle, hey, we're using a lot of glucose here for energy, so we need to bring more glucose in.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

And the way it does it is by increasing glute four transporters at the muscle.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

And I mentioned lactate levels go up during this intense exercise.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

That's very transient.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

So after about 20 minutes,

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

When exercise stops, your lactate levels go back to baseline because all these other organs, including the muscle, are consuming it so quickly.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

However, the increase in glucose for transporters stays elevated for up to 48 hours, with the first 24 hours being the most robust.

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

So you're getting a long-term effect from that signaling from lactate

FoundMyFitness
#096 How to Improve Metabolic Health with HIIT, Circadian-Timed Eating, & Sleep

back to the muscle to increase GLUT4 transporters.