Dr. Matthew B. (Matt) (likely the presenter) - Unknown
👤 PersonAppearances Over Time
Podcast Appearances
It goes back into the muscle.
It goes to the kidneys.
It goes to the liver.
And it's serving a very utilizable source of energy.
So lactate can be used and converted into...
acetyl-CoA and used by energy, by the mitochondria.
But probably one of its most important roles is as a signaling molecule.
It's a way for your muscle to connect, to communicate with other organs and other tissues.
And one of its signaling roles is back in the muscle, it's increasing the translocation of glucose-4 transporters to the cell surface of the muscles.
glute four transporters.
And so lactate gets back into the muscle.
It's basically telling the muscle, hey, we're using a lot of glucose here for energy, so we need to bring more glucose in.
And the way it does it is by increasing glute four transporters at the muscle.
And I mentioned lactate levels go up during this intense exercise.
That's very transient.
So after about 20 minutes,
When exercise stops, your lactate levels go back to baseline because all these other organs, including the muscle, are consuming it so quickly.
However, the increase in glucose for transporters stays elevated for up to 48 hours, with the first 24 hours being the most robust.
So you're getting a long-term effect from that signaling from lactate
back to the muscle to increase GLUT4 transporters.