Dr. Matthew Hill

Even that stressor can be something that brings on an episode, but cannabis very specifically, like different than any other drugs like alcohol or cigarettes, as far as I understand it, at least the temporal relationship between cannabis use and the development of a first episode can be pretty linked. Um,

But the arguments that I've always had with people in this area who are very definitive on their end of the spectrum that this is a causal relationship is – First of all, we have a few things that like I would leverage as kind of real world evidence that makes this questionable.

But the arguments that I've always had with people in this area who are very definitive on their end of the spectrum that this is a causal relationship is – First of all, we have a few things that like I would leverage as kind of real world evidence that makes this questionable.

But the arguments that I've always had with people in this area who are very definitive on their end of the spectrum that this is a causal relationship is – First of all, we have a few things that like I would leverage as kind of real world evidence that makes this questionable.

So the first one is like I was saying earlier in the episode, I mean, we really didn't have cannabis use in the West like as a normal thing, as one of the drugs that was part of the repertoire of what people use recreationally until like the 60s. So unlike alcohol, which has like been there for centuries, we have a little bit of a before and after. What we can look at. The Grateful Dead. Yeah.

So the first one is like I was saying earlier in the episode, I mean, we really didn't have cannabis use in the West like as a normal thing, as one of the drugs that was part of the repertoire of what people use recreationally until like the 60s. So unlike alcohol, which has like been there for centuries, we have a little bit of a before and after. What we can look at. The Grateful Dead. Yeah.

So the first one is like I was saying earlier in the episode, I mean, we really didn't have cannabis use in the West like as a normal thing, as one of the drugs that was part of the repertoire of what people use recreationally until like the 60s. So unlike alcohol, which has like been there for centuries, we have a little bit of a before and after. What we can look at. The Grateful Dead. Yeah.

So now, granted, we don't have like really good prevalence data of what schizophrenia was in the era prior. I mean, even nowadays, our prevalence data is not perfect. But if cannabis as a solitary variable was driving the genesis of schizophrenia de novo.

So now, granted, we don't have like really good prevalence data of what schizophrenia was in the era prior. I mean, even nowadays, our prevalence data is not perfect. But if cannabis as a solitary variable was driving the genesis of schizophrenia de novo.

So now, granted, we don't have like really good prevalence data of what schizophrenia was in the era prior. I mean, even nowadays, our prevalence data is not perfect. But if cannabis as a solitary variable was driving the genesis of schizophrenia de novo.

In the absence of any kind of biological predisposition or genetic predisposition, I find it very hard to believe that we wouldn't have seen a shift in the prevalence of the disease as cannabis became more mainstream and more widely used. And generally, schizophrenia rates have remained largely stable.

In the absence of any kind of biological predisposition or genetic predisposition, I find it very hard to believe that we wouldn't have seen a shift in the prevalence of the disease as cannabis became more mainstream and more widely used. And generally, schizophrenia rates have remained largely stable.

In the absence of any kind of biological predisposition or genetic predisposition, I find it very hard to believe that we wouldn't have seen a shift in the prevalence of the disease as cannabis became more mainstream and more widely used. And generally, schizophrenia rates have remained largely stable.

People can make arguments about that, better care, other things to challenge that argument, sure. So another modern perspective would be, okay, well, let's look at Canada and the States, let's say, where we have, as I said earlier, teenagers in Canada and the States, by grade 12, 35 to 40% of teenagers have at least used cannabis, somewhat sporadically.

People can make arguments about that, better care, other things to challenge that argument, sure. So another modern perspective would be, okay, well, let's look at Canada and the States, let's say, where we have, as I said earlier, teenagers in Canada and the States, by grade 12, 35 to 40% of teenagers have at least used cannabis, somewhat sporadically.

People can make arguments about that, better care, other things to challenge that argument, sure. So another modern perspective would be, okay, well, let's look at Canada and the States, let's say, where we have, as I said earlier, teenagers in Canada and the States, by grade 12, 35 to 40% of teenagers have at least used cannabis, somewhat sporadically.

And somewhere around 5%-ish are probably using almost daily. So we have... concentrated group of what would be the high-risk population here that are using at a pretty high rate. And then we compare that to somewhere like, let's say, Norway or Sweden or any of the Scandinavian countries where cannabis is like not a thing. Certainly not at a recreational level and not in teenagers.

And somewhere around 5%-ish are probably using almost daily. So we have... concentrated group of what would be the high-risk population here that are using at a pretty high rate. And then we compare that to somewhere like, let's say, Norway or Sweden or any of the Scandinavian countries where cannabis is like not a thing. Certainly not at a recreational level and not in teenagers.

And somewhere around 5%-ish are probably using almost daily. So we have... concentrated group of what would be the high-risk population here that are using at a pretty high rate. And then we compare that to somewhere like, let's say, Norway or Sweden or any of the Scandinavian countries where cannabis is like not a thing. Certainly not at a recreational level and not in teenagers.

And I mean, the use rates there are probably under 5% globally for teenagers, like probably closer to 2% or 3%. So you have two countries that have pretty similar social structures and other capacities of things. We're both Western countries. And yet, Our schizophrenia rates prevalence-wise are relatively comparable.