Dr. Matthew Hill

look at this from a somewhat, let's say, unbiased perspective where they see, you know, there's certainly some genetic architecture that relates to people either initiating cannabis use or people developing cannabis use disorder. And there's clearly some genetic architecture that relates to risk for schizophrenia.

And what these studies have found kind of across the three of them was quite similar, which was from their analysis, the directionality suggested much more that having genetic risk for schizophrenia predicted cannabis use, more so than cannabis use predicted the development of schizophrenia. Interesting.

And what these studies have found kind of across the three of them was quite similar, which was from their analysis, the directionality suggested much more that having genetic risk for schizophrenia predicted cannabis use, more so than cannabis use predicted the development of schizophrenia. Interesting.

And what these studies have found kind of across the three of them was quite similar, which was from their analysis, the directionality suggested much more that having genetic risk for schizophrenia predicted cannabis use, more so than cannabis use predicted the development of schizophrenia. Interesting.

So what that would mean is that there is some underlying biology that might be shared between a biological vulnerability to develop schizophrenia and some factor that relates to people using and or liking and or excessively using cannabis.

So what that would mean is that there is some underlying biology that might be shared between a biological vulnerability to develop schizophrenia and some factor that relates to people using and or liking and or excessively using cannabis.

So what that would mean is that there is some underlying biology that might be shared between a biological vulnerability to develop schizophrenia and some factor that relates to people using and or liking and or excessively using cannabis.

So, I mean, and this is, you know, I've debated with other researchers in the area in print and in person about the different interpretations of this. And one of the possibilities is, again, this idea of self-medication. I mean, independent of there being some underlying biological… thing that just is a third variable that explains the relationship between cannabis and schizophrenia.

So, I mean, and this is, you know, I've debated with other researchers in the area in print and in person about the different interpretations of this. And one of the possibilities is, again, this idea of self-medication. I mean, independent of there being some underlying biological… thing that just is a third variable that explains the relationship between cannabis and schizophrenia.

So, I mean, and this is, you know, I've debated with other researchers in the area in print and in person about the different interpretations of this. And one of the possibilities is, again, this idea of self-medication. I mean, independent of there being some underlying biological… thing that just is a third variable that explains the relationship between cannabis and schizophrenia.

The other possibility is self-medication. And there are some studies that suggest this and others that don't support it. Anecdotally, from having done work in the community and talked to individuals who have schizophrenia, who use cannabis, what their perspective on it is, what I've heard from a few of them is the medications that they're provided to manage the disease are

The other possibility is self-medication. And there are some studies that suggest this and others that don't support it. Anecdotally, from having done work in the community and talked to individuals who have schizophrenia, who use cannabis, what their perspective on it is, what I've heard from a few of them is the medications that they're provided to manage the disease are

The other possibility is self-medication. And there are some studies that suggest this and others that don't support it. Anecdotally, from having done work in the community and talked to individuals who have schizophrenia, who use cannabis, what their perspective on it is, what I've heard from a few of them is the medications that they're provided to manage the disease are

relatively effective at managing, let's say, the positive symptoms like hallucinations, delusions. That aspect of the disease is somewhat well managed. But then there's another component, which is the negative symptoms, which is kind of like things that, you know, abolition. So I don't like engaging in stuff. There's some anxiety, some depression, some social withdrawal. And

relatively effective at managing, let's say, the positive symptoms like hallucinations, delusions. That aspect of the disease is somewhat well managed. But then there's another component, which is the negative symptoms, which is kind of like things that, you know, abolition. So I don't like engaging in stuff. There's some anxiety, some depression, some social withdrawal. And

relatively effective at managing, let's say, the positive symptoms like hallucinations, delusions. That aspect of the disease is somewhat well managed. But then there's another component, which is the negative symptoms, which is kind of like things that, you know, abolition. So I don't like engaging in stuff. There's some anxiety, some depression, some social withdrawal. And

A lot of the medications don't manage that component of the disease, and they have said that they find cannabis helps that side of it, or it helps them de-arouse a little bit. Even though a lot of them recognize it may trigger the development of some of the positive symptoms, they feel that they don't have any tool in their kit to manage the negative symptoms.

A lot of the medications don't manage that component of the disease, and they have said that they find cannabis helps that side of it, or it helps them de-arouse a little bit. Even though a lot of them recognize it may trigger the development of some of the positive symptoms, they feel that they don't have any tool in their kit to manage the negative symptoms.

A lot of the medications don't manage that component of the disease, and they have said that they find cannabis helps that side of it, or it helps them de-arouse a little bit. Even though a lot of them recognize it may trigger the development of some of the positive symptoms, they feel that they don't have any tool in their kit to manage the negative symptoms.

And so it could be, in my mind, when I look at that, it could be a bit of a vicious cycle, where someone's using it to kind of band-aid one aspect, but making other aspects of the disease worse at the same time. So it can get very complicated, but...