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Dr. Matthew Hill

πŸ‘€ Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And this is something I think that's been seen a fair amount is there is some co-relationship in the way that these track at a heredity level. And so I don't know that area really well enough to be able to comment on it. And from the cannabis perspective, bipolar is definitely much less studied and focused on than schizophrenia is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And this is something I think that's been seen a fair amount is there is some co-relationship in the way that these track at a heredity level. And so I don't know that area really well enough to be able to comment on it. And from the cannabis perspective, bipolar is definitely much less studied and focused on than schizophrenia is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And this is something I think that's been seen a fair amount is there is some co-relationship in the way that these track at a heredity level. And so I don't know that area really well enough to be able to comment on it. And from the cannabis perspective, bipolar is definitely much less studied and focused on than schizophrenia is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But I think also to the comment about the high THC thing, I think this is the other part of the argument that's emerged out of this. And this is the other part where I see a lot of the causality arguments kind of crumble onto themselves to some degree. And there's been others who've made these very similar arguments to what I'm making here, which is

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But I think also to the comment about the high THC thing, I think this is the other part of the argument that's emerged out of this. And this is the other part where I see a lot of the causality arguments kind of crumble onto themselves to some degree. And there's been others who've made these very similar arguments to what I'm making here, which is

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But I think also to the comment about the high THC thing, I think this is the other part of the argument that's emerged out of this. And this is the other part where I see a lot of the causality arguments kind of crumble onto themselves to some degree. And there's been others who've made these very similar arguments to what I'm making here, which is

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So the push that came out of this, out of the UK at least, was much more that it's this high potency kind of skunk cannabis they referred to, which first of all was based on a smell, which they didn't really hadn't done a lot of analytics on. So it was people make the assumption if it smells stronger, it's more potent cannabis. That's not really true because THC doesn't dictate the odor.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So the push that came out of this, out of the UK at least, was much more that it's this high potency kind of skunk cannabis they referred to, which first of all was based on a smell, which they didn't really hadn't done a lot of analytics on. So it was people make the assumption if it smells stronger, it's more potent cannabis. That's not really true because THC doesn't dictate the odor.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So the push that came out of this, out of the UK at least, was much more that it's this high potency kind of skunk cannabis they referred to, which first of all was based on a smell, which they didn't really hadn't done a lot of analytics on. So it was people make the assumption if it smells stronger, it's more potent cannabis. That's not really true because THC doesn't dictate the odor.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So I was saying more of a terpene thing, but certainly I'm sure some of the skunk cannabis they're referring to is high potency cannabis. And so the analysis on this, if you actually go back to those papers and read, is they often use like hash or low potency cannabis as their control where they show no association with cannabis.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So I was saying more of a terpene thing, but certainly I'm sure some of the skunk cannabis they're referring to is high potency cannabis. And so the analysis on this, if you actually go back to those papers and read, is they often use like hash or low potency cannabis as their control where they show no association with cannabis.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So I was saying more of a terpene thing, but certainly I'm sure some of the skunk cannabis they're referring to is high potency cannabis. And so the analysis on this, if you actually go back to those papers and read, is they often use like hash or low potency cannabis as their control where they show no association with cannabis.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so that's what's used this argument that it's the high potency cannabis that has driven this. So now the problem with this argument, in my view, again, I look for what is the – Answer that fits in with the data, like what's the most parsimonious explanation here that everything can be explained by?

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so that's what's used this argument that it's the high potency cannabis that has driven this. So now the problem with this argument, in my view, again, I look for what is the – Answer that fits in with the data, like what's the most parsimonious explanation here that everything can be explained by?

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so that's what's used this argument that it's the high potency cannabis that has driven this. So now the problem with this argument, in my view, again, I look for what is the – Answer that fits in with the data, like what's the most parsimonious explanation here that everything can be explained by?

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so the problem with that argument is if you look at the cannabis schizophrenia literature, everything goes back to this one 1987 Lancet paper out of Sweden, where in that paper, they essentially looked at, they have really detailed life records and health records, and this was Swedish conscripts.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so the problem with that argument is if you look at the cannabis schizophrenia literature, everything goes back to this one 1987 Lancet paper out of Sweden, where in that paper, they essentially looked at, they have really detailed life records and health records, and this was Swedish conscripts.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so the problem with that argument is if you look at the cannabis schizophrenia literature, everything goes back to this one 1987 Lancet paper out of Sweden, where in that paper, they essentially looked at, they have really detailed life records and health records, and this was Swedish conscripts.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And they essentially found that if someone had used cannabis, the rate, the risk of developing schizophrenia had gone up and up. And so this was based on a cohort of people when it was published in 87 that the data would have been collected through like the 60s, 70s, early 80s. So we're talking about Sweden and cannabis together.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And they essentially found that if someone had used cannabis, the rate, the risk of developing schizophrenia had gone up and up. And so this was based on a cohort of people when it was published in 87 that the data would have been collected through like the 60s, 70s, early 80s. So we're talking about Sweden and cannabis together.