Dr. Matthew Hill

And you can take a sativa and an indica that have virtually identical levels of THC and yet people will report very different intoxicating states that come out of that.

And you can take a sativa and an indica that have virtually identical levels of THC and yet people will report very different intoxicating states that come out of that.

And you can take a sativa and an indica that have virtually identical levels of THC and yet people will report very different intoxicating states that come out of that.

I mean, I have to believe the majority of that's an expectancy bias. I have a hard time believing that these things are really driven by fundamental biological differences within... Because anything else that's... I mean, that's the thing, like... Sure.

I mean, I have to believe the majority of that's an expectancy bias. I have a hard time believing that these things are really driven by fundamental biological differences within... Because anything else that's... I mean, that's the thing, like... Sure.

I mean, I have to believe the majority of that's an expectancy bias. I have a hard time believing that these things are really driven by fundamental biological differences within... Because anything else that's... I mean, that's the thing, like... Sure.

Some of the labs now, there is a movement to start looking at, can certain compositions of other things in cannabis start to maybe modulate or influence? This is called, like I think I've said this before, the entourage effect, this idea that THC alone might do one thing, but then layering in other things. Terpenes or minor cannabinoids may influence that effect. That is a theory.

Some of the labs now, there is a movement to start looking at, can certain compositions of other things in cannabis start to maybe modulate or influence? This is called, like I think I've said this before, the entourage effect, this idea that THC alone might do one thing, but then layering in other things. Terpenes or minor cannabinoids may influence that effect. That is a theory.

Some of the labs now, there is a movement to start looking at, can certain compositions of other things in cannabis start to maybe modulate or influence? This is called, like I think I've said this before, the entourage effect, this idea that THC alone might do one thing, but then layering in other things. Terpenes or minor cannabinoids may influence that effect. That is a theory.

That's not a thing that we know definitively in any way. And in fact, there's virtually no research that's ever been done to test this.

That's not a thing that we know definitively in any way. And in fact, there's virtually no research that's ever been done to test this.

That's not a thing that we know definitively in any way. And in fact, there's virtually no research that's ever been done to test this.

There's some stuff that's starting to come out now, like Ryan Vandery at Hopkins recently published a paper where they kind of, in a dose-dependent manner, added limonene, which is one of these terpenes, like I said, I think gives it like a citrusy odor, into the THC and did find at a really high dose, Probably a dose that I don't think you could actually find in cannabis.

There's some stuff that's starting to come out now, like Ryan Vandery at Hopkins recently published a paper where they kind of, in a dose-dependent manner, added limonene, which is one of these terpenes, like I said, I think gives it like a citrusy odor, into the THC and did find at a really high dose, Probably a dose that I don't think you could actually find in cannabis.

There's some stuff that's starting to come out now, like Ryan Vandery at Hopkins recently published a paper where they kind of, in a dose-dependent manner, added limonene, which is one of these terpenes, like I said, I think gives it like a citrusy odor, into the THC and did find at a really high dose, Probably a dose that I don't think you could actually find in cannabis.

It's a little bit higher than what you would have gotten there. But limonene did seem to be able to curb the ability of high dose THC to make someone feel anxious. And this was done in a blinded manner. So there's, I think, some validity to the interaction, whether that's occurring in cannabis, naturally, because of the levels of THC to limonene, I don't know.

It's a little bit higher than what you would have gotten there. But limonene did seem to be able to curb the ability of high dose THC to make someone feel anxious. And this was done in a blinded manner. So there's, I think, some validity to the interaction, whether that's occurring in cannabis, naturally, because of the levels of THC to limonene, I don't know.

It's a little bit higher than what you would have gotten there. But limonene did seem to be able to curb the ability of high dose THC to make someone feel anxious. And this was done in a blinded manner. So there's, I think, some validity to the interaction, whether that's occurring in cannabis, naturally, because of the levels of THC to limonene, I don't know.

But it really was one of the first demonstrations that adding in a terpene could actually influence a component of the intoxicated state in a blinded manner, I think is interesting. And Ziva Cooper, who's here at UCLA, is doing some work with beta-caryophyllene, which is probably... probably the second most abundant terpene, I think, from Nick Chikomas' work.

But it really was one of the first demonstrations that adding in a terpene could actually influence a component of the intoxicated state in a blinded manner, I think is interesting. And Ziva Cooper, who's here at UCLA, is doing some work with beta-caryophyllene, which is probably... probably the second most abundant terpene, I think, from Nick Chikomas' work.