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Dr. Matthew Hill

πŸ‘€ Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I just am remiss to believe this until I see some blinded data because I think outside of that, we know how powerful an expectancy bias is. So it makes it very, very challenging to make any kind of firm statements. And so kind of in the context of like how you introduced this, that was – again, I think like one of the issues that I took with the other podcast was because –

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I just am remiss to believe this until I see some blinded data because I think outside of that, we know how powerful an expectancy bias is. So it makes it very, very challenging to make any kind of firm statements. And so kind of in the context of like how you introduced this, that was – again, I think like one of the issues that I took with the other podcast was because –

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

As you've said, I understand the thought process you went through. Like, you know, you had this paper where people were reporting subjective effects. There's some neuroimaging data that's been done with cannabis. You kind of said, okay, this is what that was, and that was what sativa did versus this is what indica did.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

As you've said, I understand the thought process you went through. Like, you know, you had this paper where people were reporting subjective effects. There's some neuroimaging data that's been done with cannabis. You kind of said, okay, this is what that was, and that was what sativa did versus this is what indica did.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

As you've said, I understand the thought process you went through. Like, you know, you had this paper where people were reporting subjective effects. There's some neuroimaging data that's been done with cannabis. You kind of said, okay, this is what that was, and that was what sativa did versus this is what indica did.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, I would say that's definitely not true nowadays. That pre-legalization anywhere outside of Colorado, that was true. People were gravitating there towards it.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, I would say that's definitely not true nowadays. That pre-legalization anywhere outside of Colorado, that was true. People were gravitating there towards it.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, I would say that's definitely not true nowadays. That pre-legalization anywhere outside of Colorado, that was true. People were gravitating there towards it.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, I mean, the first thing that's interesting that I think a lot of people don't understand about CBD is CBD doesn't really exist in any form of street cannabis, and it hasn't for a very long time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, I mean, the first thing that's interesting that I think a lot of people don't understand about CBD is CBD doesn't really exist in any form of street cannabis, and it hasn't for a very long time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, I mean, the first thing that's interesting that I think a lot of people don't understand about CBD is CBD doesn't really exist in any form of street cannabis, and it hasn't for a very long time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

There's some. There's very, very low levels of CBD. And the reason that is, is because THC and CBD are both made from the same precursor molecule. And which direction it goes in is based purely on which synthetic enzyme converts it to either THC or CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

There's some. There's very, very low levels of CBD. And the reason that is, is because THC and CBD are both made from the same precursor molecule. And which direction it goes in is based purely on which synthetic enzyme converts it to either THC or CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

There's some. There's very, very low levels of CBD. And the reason that is, is because THC and CBD are both made from the same precursor molecule. And which direction it goes in is based purely on which synthetic enzyme converts it to either THC or CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so as people have clearly chased THC and wanted cannabis that's rich in THC, and so cannabis has been bred to become higher content in THC, by default, CBD has been bred out of the plant. And it has largely been bred out of the plant for quite some time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so as people have clearly chased THC and wanted cannabis that's rich in THC, and so cannabis has been bred to become higher content in THC, by default, CBD has been bred out of the plant. And it has largely been bred out of the plant for quite some time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so as people have clearly chased THC and wanted cannabis that's rich in THC, and so cannabis has been bred to become higher content in THC, by default, CBD has been bred out of the plant. And it has largely been bred out of the plant for quite some time.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so this – I always find it interesting that there's this community that's like, oh, well, THC is the recreational cannabis and CBD is the medical cannabis. And I'm always like, that's bizarre because historically there's always been like THC has been what people have bred cannabis for.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so this – I always find it interesting that there's this community that's like, oh, well, THC is the recreational cannabis and CBD is the medical cannabis. And I'm always like, that's bizarre because historically there's always been like THC has been what people have bred cannabis for.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so this – I always find it interesting that there's this community that's like, oh, well, THC is the recreational cannabis and CBD is the medical cannabis. And I'm always like, that's bizarre because historically there's always been like THC has been what people have bred cannabis for.