Dr. Matthew Hill

And again, this is me theorizing what I think it could be based on what we understand to some degree about how it affects cardiovascular function. There are occasionally people who have reported having like elevated blood pressure. I mean, some of that also could be from like an anxiety state or whatnot coming around.

But the typical response, and this is usually driven by cannabinoid receptors that are in the vascular beds themselves, that it causes a vasodilatory response. And so that is usually the first step. The second is the uptick in the heart rate. So you get these kind of effects over time. There's some work looking at like vascular stiffness that can evolve over time.

But the typical response, and this is usually driven by cannabinoid receptors that are in the vascular beds themselves, that it causes a vasodilatory response. And so that is usually the first step. The second is the uptick in the heart rate. So you get these kind of effects over time. There's some work looking at like vascular stiffness that can evolve over time.

But the typical response, and this is usually driven by cannabinoid receptors that are in the vascular beds themselves, that it causes a vasodilatory response. And so that is usually the first step. The second is the uptick in the heart rate. So you get these kind of effects over time. There's some work looking at like vascular stiffness that can evolve over time.

And cannabis users, there's some evidence to suggest that you might get more of that emerging. And so again, that could relate to a vulnerability to have strokes or other kind of cardiovascular events in that sense. So I think the issue in terms of like why it is more difficult for us to say anything definitively at this point is just obviously the timeline of this.

And cannabis users, there's some evidence to suggest that you might get more of that emerging. And so again, that could relate to a vulnerability to have strokes or other kind of cardiovascular events in that sense. So I think the issue in terms of like why it is more difficult for us to say anything definitively at this point is just obviously the timeline of this.

And cannabis users, there's some evidence to suggest that you might get more of that emerging. And so again, that could relate to a vulnerability to have strokes or other kind of cardiovascular events in that sense. So I think the issue in terms of like why it is more difficult for us to say anything definitively at this point is just obviously the timeline of this.

I mean, you know, cigarette smoking was an easier thing to establish in that context because, you know, once antibiotics and medicine advanced in like the 40s and the 30s and stuff and people started living longer, you started seeing a lot of these effects of cigarette smoking emerge.

I mean, you know, cigarette smoking was an easier thing to establish in that context because, you know, once antibiotics and medicine advanced in like the 40s and the 30s and stuff and people started living longer, you started seeing a lot of these effects of cigarette smoking emerge.

I mean, you know, cigarette smoking was an easier thing to establish in that context because, you know, once antibiotics and medicine advanced in like the 40s and the 30s and stuff and people started living longer, you started seeing a lot of these effects of cigarette smoking emerge.

Oh, I know. It's wild.

Oh, I know. It's wild.

Oh, I know. It's wild.

I mean my grandparents grew up in Belfast. They had smoked for years and they had even said like when they were younger, doctors would say, oh, have a cigarette after a meal. It promotes digestion. So it's kind of wild to hear that stuff when you think of how cigarettes are viewed nowadays. But –

I mean my grandparents grew up in Belfast. They had smoked for years and they had even said like when they were younger, doctors would say, oh, have a cigarette after a meal. It promotes digestion. So it's kind of wild to hear that stuff when you think of how cigarettes are viewed nowadays. But –

I mean my grandparents grew up in Belfast. They had smoked for years and they had even said like when they were younger, doctors would say, oh, have a cigarette after a meal. It promotes digestion. So it's kind of wild to hear that stuff when you think of how cigarettes are viewed nowadays. But –

It is, I don't think we've kind of been able to track this long enough to be able to say with certainty what we're seeing. But I think there's, like if people ask me about risks and harms of cannabis, the first thing I always say is, you know, schizophrenia and bipolar. Those are the main concern areas, I think, where you want to avoid cannabis.

It is, I don't think we've kind of been able to track this long enough to be able to say with certainty what we're seeing. But I think there's, like if people ask me about risks and harms of cannabis, the first thing I always say is, you know, schizophrenia and bipolar. Those are the main concern areas, I think, where you want to avoid cannabis.

It is, I don't think we've kind of been able to track this long enough to be able to say with certainty what we're seeing. But I think there's, like if people ask me about risks and harms of cannabis, the first thing I always say is, you know, schizophrenia and bipolar. Those are the main concern areas, I think, where you want to avoid cannabis.

And I would also say if anyone has cardiovascular issues, they should avoid cannabis just because that's more of like I would say a being safe because I don't know how to actually explicitly say what I would say the harms associated with it are. But I think there is something there. I've seen enough evidence that's like starting to coalesce into a story that's like there's something here. Mm-hmm.