Dr. Matthew Hill

Yeah, so the pain thing, I think, is a central one. And that's one of the only ones that there's a little bit of actual research on. Most of it's either with isolated THC. I think there's one or two studies that have actually looked at smoke cannabis and found small signals of benefit. But so anxiety is an interesting one.

Yeah, so the pain thing, I think, is a central one. And that's one of the only ones that there's a little bit of actual research on. Most of it's either with isolated THC. I think there's one or two studies that have actually looked at smoke cannabis and found small signals of benefit. But so anxiety is an interesting one.

And so, I mean, obviously, this is more near and dear to my heart because I study stress and anxiety as my primary area and cannabinoids and endocannabinoids in that space. And, yeah, you look at questionnaire-based – studies about why people smoke cannabis and like 85% of them will say because it reduces stress and it makes me feel less anxious.

And so, I mean, obviously, this is more near and dear to my heart because I study stress and anxiety as my primary area and cannabinoids and endocannabinoids in that space. And, yeah, you look at questionnaire-based – studies about why people smoke cannabis and like 85% of them will say because it reduces stress and it makes me feel less anxious.

And so, I mean, obviously, this is more near and dear to my heart because I study stress and anxiety as my primary area and cannabinoids and endocannabinoids in that space. And, yeah, you look at questionnaire-based – studies about why people smoke cannabis and like 85% of them will say because it reduces stress and it makes me feel less anxious.

I mean, that was like a big impetus as to why we started studying endocannabinoid regulation of it because similar to feeding and pain where we know endocannabinoids are involved in regulated feeding circuits and endocannabinoids are also integrated into pain circuitry and can provide some endogenous analgesic signals.

I mean, that was like a big impetus as to why we started studying endocannabinoid regulation of it because similar to feeding and pain where we know endocannabinoids are involved in regulated feeding circuits and endocannabinoids are also integrated into pain circuitry and can provide some endogenous analgesic signals.

I mean, that was like a big impetus as to why we started studying endocannabinoid regulation of it because similar to feeding and pain where we know endocannabinoids are involved in regulated feeding circuits and endocannabinoids are also integrated into pain circuitry and can provide some endogenous analgesic signals.

We figured the same was going to be true for stress and anxiety, which to some degree it is. But it's very complicated because it can be, like I said before, biphasic where some lower doses are anxiolytic, higher doses can promote anxiety. But for the majority of people who use cannabis regularly, it's because it helps reduce anxiety.

We figured the same was going to be true for stress and anxiety, which to some degree it is. But it's very complicated because it can be, like I said before, biphasic where some lower doses are anxiolytic, higher doses can promote anxiety. But for the majority of people who use cannabis regularly, it's because it helps reduce anxiety.

We figured the same was going to be true for stress and anxiety, which to some degree it is. But it's very complicated because it can be, like I said before, biphasic where some lower doses are anxiolytic, higher doses can promote anxiety. But for the majority of people who use cannabis regularly, it's because it helps reduce anxiety.

Now, whether that would hold weight in a clinical trial is a different story. There is some old evidence from like

Now, whether that would hold weight in a clinical trial is a different story. There is some old evidence from like

Now, whether that would hold weight in a clinical trial is a different story. There is some old evidence from like

I'd say the 70s, early 80s, where they were using synthetic forms of THC like nabilone, which is something you can get in Canada, or marinol or dronabinol, which I think is what's accessible in the States, where they did find some evidence to suggest it was on par with like a benzodiazepine, like diazepam or something.

I'd say the 70s, early 80s, where they were using synthetic forms of THC like nabilone, which is something you can get in Canada, or marinol or dronabinol, which I think is what's accessible in the States, where they did find some evidence to suggest it was on par with like a benzodiazepine, like diazepam or something.

I'd say the 70s, early 80s, where they were using synthetic forms of THC like nabilone, which is something you can get in Canada, or marinol or dronabinol, which I think is what's accessible in the States, where they did find some evidence to suggest it was on par with like a benzodiazepine, like diazepam or something.

I can't remember exactly what the comparator they'd used in there, but there was some evidence for... there being some anti-anxiety properties of THC. And that tracks generally well with the self-reported literature that's out there. Now, whether that's the same as an ability to have benefit in something like PTSD is a different question.

I can't remember exactly what the comparator they'd used in there, but there was some evidence for... there being some anti-anxiety properties of THC. And that tracks generally well with the self-reported literature that's out there. Now, whether that's the same as an ability to have benefit in something like PTSD is a different question.

I can't remember exactly what the comparator they'd used in there, but there was some evidence for... there being some anti-anxiety properties of THC. And that tracks generally well with the self-reported literature that's out there. Now, whether that's the same as an ability to have benefit in something like PTSD is a different question.