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Dr. Matthew Hill

πŸ‘€ Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Maybe for some people, this is, again, this is theoretical, so I don't know how much of a spectrum there is if there are people that are at this low end, but certainly I think from the animal literature, there's some foundation for making a theory that's similar to what you're saying, which is maybe some people are trying to fill in a gap of something that's deficient in them, and therefore that can help them feel less anxious.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And that, again, may be very different than someone who is very anxious for different reasons or has normal endocannabinoid function or something else might be at play there. So- Very interesting. Yeah, I think it could explain some of the heterogeneity that exists out there for sure, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And that, again, may be very different than someone who is very anxious for different reasons or has normal endocannabinoid function or something else might be at play there. So- Very interesting. Yeah, I think it could explain some of the heterogeneity that exists out there for sure, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And that, again, may be very different than someone who is very anxious for different reasons or has normal endocannabinoid function or something else might be at play there. So- Very interesting. Yeah, I think it could explain some of the heterogeneity that exists out there for sure, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, we have definitely found in human populations through work I've done with a lot of clinical collaborators and others, like... We look at endocannabinoids in the blood, and it's not in the brain, but they are lipids that can move pretty easily back and forth.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, we have definitely found in human populations through work I've done with a lot of clinical collaborators and others, like... We look at endocannabinoids in the blood, and it's not in the brain, but they are lipids that can move pretty easily back and forth.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, I mean, we have definitely found in human populations through work I've done with a lot of clinical collaborators and others, like... We look at endocannabinoids in the blood, and it's not in the brain, but they are lipids that can move pretty easily back and forth.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And we have found relationships between peripheral endocannabinoid levels and mood states, both anxiety and kind of depressive measures, which does somewhat relate to... The possibility that this could be real, we don't know. It's been hard, obviously, for various reasons to really track this. But we've never looked at an anxiety disorder population.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And we have found relationships between peripheral endocannabinoid levels and mood states, both anxiety and kind of depressive measures, which does somewhat relate to... The possibility that this could be real, we don't know. It's been hard, obviously, for various reasons to really track this. But we've never looked at an anxiety disorder population.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And we have found relationships between peripheral endocannabinoid levels and mood states, both anxiety and kind of depressive measures, which does somewhat relate to... The possibility that this could be real, we don't know. It's been hard, obviously, for various reasons to really track this. But we've never looked at an anxiety disorder population.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

We've done some work with post-traumatic stress disorder populations. There's been work in depression populations that have found some relationships that are pretty similar. So it's certainly a possibility. But again, this is all like our theory at this point. So we'll see as things kind of move forward if they pan out. But yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

We've done some work with post-traumatic stress disorder populations. There's been work in depression populations that have found some relationships that are pretty similar. So it's certainly a possibility. But again, this is all like our theory at this point. So we'll see as things kind of move forward if they pan out. But yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

We've done some work with post-traumatic stress disorder populations. There's been work in depression populations that have found some relationships that are pretty similar. So it's certainly a possibility. But again, this is all like our theory at this point. So we'll see as things kind of move forward if they pan out. But yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Thanks. And I think it's also important. I think it's good, as you had said, that like for people to see that scientists can have disagreements. Absolutely. I think it's important. I think it's good that you kind of provided me an opportunity to correct the record and did so in a very appropriate manner. I think this was a great discussion for people to understand different perspectives.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Thanks. And I think it's also important. I think it's good, as you had said, that like for people to see that scientists can have disagreements. Absolutely. I think it's important. I think it's good that you kind of provided me an opportunity to correct the record and did so in a very appropriate manner. I think this was a great discussion for people to understand different perspectives.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Thanks. And I think it's also important. I think it's good, as you had said, that like for people to see that scientists can have disagreements. Absolutely. I think it's important. I think it's good that you kind of provided me an opportunity to correct the record and did so in a very appropriate manner. I think this was a great discussion for people to understand different perspectives.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Also good to highlight. where it was that I had had issue with your previous podcast. And I think the discussions that came out of that were for the better. So that's all the best. And hopefully if there's other contentious issues that happen down the road, similar things, move forward and you chat with people. Oh, I always, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Also good to highlight. where it was that I had had issue with your previous podcast. And I think the discussions that came out of that were for the better. So that's all the best. And hopefully if there's other contentious issues that happen down the road, similar things, move forward and you chat with people. Oh, I always, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Also good to highlight. where it was that I had had issue with your previous podcast. And I think the discussions that came out of that were for the better. So that's all the best. And hopefully if there's other contentious issues that happen down the road, similar things, move forward and you chat with people. Oh, I always, yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And I think it's really good for people in the public to know this is how science progresses. This is, you know, someone says something, someone disagrees with it. You get an opportunity to clarify things. And I think that that's really good just to move things forward. So I think that was a good process that we've gone through.