Dr. Matthew Walker
π€ SpeakerAppearances Over Time
Podcast Appearances
What do you sort of come to think about here?
What do you sort of come to think about here?
What do you sort of come to think about here?
Yeah, I think the first thing to note is that if Any of these supplements or any supplement stacks that are out there that promise you the royal road to resplendent sleep, if they really were doing what they claim, the drug companies would have been all over them 20 years ago and would find analogs and would have been making billions of dollars from them.
Yeah, I think the first thing to note is that if Any of these supplements or any supplement stacks that are out there that promise you the royal road to resplendent sleep, if they really were doing what they claim, the drug companies would have been all over them 20 years ago and would find analogs and would have been making billions of dollars from them.
Yeah, I think the first thing to note is that if Any of these supplements or any supplement stacks that are out there that promise you the royal road to resplendent sleep, if they really were doing what they claim, the drug companies would have been all over them 20 years ago and would find analogs and would have been making billions of dollars from them.
The fact that they've left them to the wayside tells you a lot about really what their efficacy is. And the drug companies are ruthless, but it took George Lucas, I think something like 30 or 40 years to amass about 4 billion in profit from the Star Wars franchise. It took Ambien 21 months to do that.
The fact that they've left them to the wayside tells you a lot about really what their efficacy is. And the drug companies are ruthless, but it took George Lucas, I think something like 30 or 40 years to amass about 4 billion in profit from the Star Wars franchise. It took Ambien 21 months to do that.
The fact that they've left them to the wayside tells you a lot about really what their efficacy is. And the drug companies are ruthless, but it took George Lucas, I think something like 30 or 40 years to amass about 4 billion in profit from the Star Wars franchise. It took Ambien 21 months to do that.
So they know that these drugs, if they are out there and any molecules like these supplements, if they are good sleep aids, they will be very strategic. Melatonin, I think, certainly over here, it's so easily purchased. You go down, you know, any grocery store and in the health food section, there's this big purple subsection and that's the melatonin section.
So they know that these drugs, if they are out there and any molecules like these supplements, if they are good sleep aids, they will be very strategic. Melatonin, I think, certainly over here, it's so easily purchased. You go down, you know, any grocery store and in the health food section, there's this big purple subsection and that's the melatonin section.
So they know that these drugs, if they are out there and any molecules like these supplements, if they are good sleep aids, they will be very strategic. Melatonin, I think, certainly over here, it's so easily purchased. You go down, you know, any grocery store and in the health food section, there's this big purple subsection and that's the melatonin section.
And you've got 10 milligrams, 20 milligrams, I've seen 50 milligrams. Firstly, 5 milligrams, 10, 20 milligrams, these are what we call supraphysiological doses, meaning that they are levels of melatonin that your body would never naturally release far higher than your body's natural tendency. So the fear here, although there are some studies that people have argued that
And you've got 10 milligrams, 20 milligrams, I've seen 50 milligrams. Firstly, 5 milligrams, 10, 20 milligrams, these are what we call supraphysiological doses, meaning that they are levels of melatonin that your body would never naturally release far higher than your body's natural tendency. So the fear here, although there are some studies that people have argued that
And you've got 10 milligrams, 20 milligrams, I've seen 50 milligrams. Firstly, 5 milligrams, 10, 20 milligrams, these are what we call supraphysiological doses, meaning that they are levels of melatonin that your body would never naturally release far higher than your body's natural tendency. So the fear here, although there are some studies that people have argued that
This is not the case, but the fear is, just like testosterone replacement, at some point your testes, if you're exogenously injecting, will just stop producing innate testosterone, and once they stop, they don't restart.
This is not the case, but the fear is, just like testosterone replacement, at some point your testes, if you're exogenously injecting, will just stop producing innate testosterone, and once they stop, they don't restart.
This is not the case, but the fear is, just like testosterone replacement, at some point your testes, if you're exogenously injecting, will just stop producing innate testosterone, and once they stop, they don't restart.
The worry is the same with your pineal gland, which is going to release melatonin, that if you keep exogenously giving your brain vast amounts, it says, well, you're giving it to me, so I don't need to produce it anymore. And once it stops, does it ever restart? There are some data where they looked at an individual who was blind.
The worry is the same with your pineal gland, which is going to release melatonin, that if you keep exogenously giving your brain vast amounts, it says, well, you're giving it to me, so I don't need to produce it anymore. And once it stops, does it ever restart? There are some data where they looked at an individual who was blind.