Dr. Matthew Walker

And it only improved your sleep efficiency by about 2.2%. So again, largely trivial. Now, I think, however, despite touting those statistics, I think there is a subset of people for whom melatonin is sleep generating. And therefore, melatonin is not just the starting official. It's also one of the racers. And we don't yet understand why.

And it only improved your sleep efficiency by about 2.2%. So again, largely trivial. Now, I think, however, despite touting those statistics, I think there is a subset of people for whom melatonin is sleep generating. And therefore, melatonin is not just the starting official. It's also one of the racers. And we don't yet understand why.

I think one of the ways that melatonin could be a sleep generating agent... and this will bring me back to CBD in a second, is that melatonin can make you cold. Melatonin has the ability to produce not hypothermia, don't worry about that, but it will drop your core body temperature a little bit.

I think one of the ways that melatonin could be a sleep generating agent... and this will bring me back to CBD in a second, is that melatonin can make you cold. Melatonin has the ability to produce not hypothermia, don't worry about that, but it will drop your core body temperature a little bit.

I think one of the ways that melatonin could be a sleep generating agent... and this will bring me back to CBD in a second, is that melatonin can make you cold. Melatonin has the ability to produce not hypothermia, don't worry about that, but it will drop your core body temperature a little bit.

And it turns out that we do need to drop our brain and core body temperature by about one degree Celsius to fall asleep and stay asleep. It's a reason that it's so hard on those summer nights when it's brutally hot and you've got no air conditioning. You can almost not fall asleep despite how tired you are in a warm room. But in a cold room, you typically can sleep.

And it turns out that we do need to drop our brain and core body temperature by about one degree Celsius to fall asleep and stay asleep. It's a reason that it's so hard on those summer nights when it's brutally hot and you've got no air conditioning. You can almost not fall asleep despite how tired you are in a warm room. But in a cold room, you typically can sleep.

And it turns out that we do need to drop our brain and core body temperature by about one degree Celsius to fall asleep and stay asleep. It's a reason that it's so hard on those summer nights when it's brutally hot and you've got no air conditioning. You can almost not fall asleep despite how tired you are in a warm room. But in a cold room, you typically can sleep.

It's always because the cold room is at least taking you in the right temperature direction for good sleep as melatonin in some individuals may be mildly hypothermic and move you in that direction. So I think that's, I'm fascinated by that and I want to pick that apart. But for most people, firstly, it's not going to move the needle.

It's always because the cold room is at least taking you in the right temperature direction for good sleep as melatonin in some individuals may be mildly hypothermic and move you in that direction. So I think that's, I'm fascinated by that and I want to pick that apart. But for most people, firstly, it's not going to move the needle.

It's always because the cold room is at least taking you in the right temperature direction for good sleep as melatonin in some individuals may be mildly hypothermic and move you in that direction. So I think that's, I'm fascinated by that and I want to pick that apart. But for most people, firstly, it's not going to move the needle.

That's the reason that no one, no doctor has ever prescribed melatonin for people with insomnia. You have to have a circadian disruptive clinical syndrome causing the insomnia to receive melatonin. That's where it can be helpful. The other thing about, or two other things about melatonin, if you could go down that purple aisle, now a large part of it is dedicated to pediatric melatonin for kids.

That's the reason that no one, no doctor has ever prescribed melatonin for people with insomnia. You have to have a circadian disruptive clinical syndrome causing the insomnia to receive melatonin. That's where it can be helpful. The other thing about, or two other things about melatonin, if you could go down that purple aisle, now a large part of it is dedicated to pediatric melatonin for kids.

That's the reason that no one, no doctor has ever prescribed melatonin for people with insomnia. You have to have a circadian disruptive clinical syndrome causing the insomnia to receive melatonin. That's where it can be helpful. The other thing about, or two other things about melatonin, if you could go down that purple aisle, now a large part of it is dedicated to pediatric melatonin for kids.

And what we know is that melatonin is a bioactive hormone. We did some work and we were looking at great scientist Craig Canepari at Yale, and we spoke with the FDA about this. Admissions to the hospital for melatonin poisonous overdose have increased by 503% in the past 10 years. which is a stunning statistic.

And what we know is that melatonin is a bioactive hormone. We did some work and we were looking at great scientist Craig Canepari at Yale, and we spoke with the FDA about this. Admissions to the hospital for melatonin poisonous overdose have increased by 503% in the past 10 years. which is a stunning statistic.

And what we know is that melatonin is a bioactive hormone. We did some work and we were looking at great scientist Craig Canepari at Yale, and we spoke with the FDA about this. Admissions to the hospital for melatonin poisonous overdose have increased by 503% in the past 10 years. which is a stunning statistic.

Now, granted melatonin for the most part is a largely inert compound in terms of its safety profile. But the worry with the pediatric component of melatonin nowadays from the sleep community is that studies done back in the 1980s, 70s demonstrated that in juvenile male rats, essentially male rats going through adolescence,

Now, granted melatonin for the most part is a largely inert compound in terms of its safety profile. But the worry with the pediatric component of melatonin nowadays from the sleep community is that studies done back in the 1980s, 70s demonstrated that in juvenile male rats, essentially male rats going through adolescence,

Now, granted melatonin for the most part is a largely inert compound in terms of its safety profile. But the worry with the pediatric component of melatonin nowadays from the sleep community is that studies done back in the 1980s, 70s demonstrated that in juvenile male rats, essentially male rats going through adolescence,