Dr. Matthew Walker

Yeah, when you have sleep disruption, yeah.

And Alzheimer's disease, there's some really fascinating data regarding... inflammation and Alzheimer's disease as a causal relationship now. Quite striking. Quite striking.

And Alzheimer's disease, there's some really fascinating data regarding... inflammation and Alzheimer's disease as a causal relationship now. Quite striking. Quite striking.

And Alzheimer's disease, there's some really fascinating data regarding... inflammation and Alzheimer's disease as a causal relationship now. Quite striking. Quite striking.

And so, and I think we don't yet know what's happening with tau, which is the other tau protein, which is the other sort of culprit there with inflammation. I suspect it may be the same story. It may be even more powerfully explanatory of cognition.

And so, and I think we don't yet know what's happening with tau, which is the other tau protein, which is the other sort of culprit there with inflammation. I suspect it may be the same story. It may be even more powerfully explanatory of cognition.

And so, and I think we don't yet know what's happening with tau, which is the other tau protein, which is the other sort of culprit there with inflammation. I suspect it may be the same story. It may be even more powerfully explanatory of cognition.

But, you know, it's all of this just once again teaches us, I think you and I, maybe people listening that for so long in medicine and science, we took the a siloed organ or system-specific approach. I was a cardiologist. I was a neurologist. I was an immunologist. We are an embodied species, brain and body combined. I'm an everything-ologist. Yeah, exactly.

But, you know, it's all of this just once again teaches us, I think you and I, maybe people listening that for so long in medicine and science, we took the a siloed organ or system-specific approach. I was a cardiologist. I was a neurologist. I was an immunologist. We are an embodied species, brain and body combined. I'm an everything-ologist. Yeah, exactly.

But, you know, it's all of this just once again teaches us, I think you and I, maybe people listening that for so long in medicine and science, we took the a siloed organ or system-specific approach. I was a cardiologist. I was a neurologist. I was an immunologist. We are an embodied species, brain and body combined. I'm an everything-ologist. Yeah, exactly.

And that's what, if your doctor says that,

And that's what, if your doctor says that,

And that's what, if your doctor says that,

Fundamental. Yeah. I mean, and during sleep, we have a metabolic reduction. Part of the... One of perhaps the restorative functions of sleep is to have a metabolic downturn to a degree. But I think the other point is there is... You spoke about all of these different, I'm a multi-system doctor.

Fundamental. Yeah. I mean, and during sleep, we have a metabolic reduction. Part of the... One of perhaps the restorative functions of sleep is to have a metabolic downturn to a degree. But I think the other point is there is... You spoke about all of these different, I'm a multi-system doctor.

Fundamental. Yeah. I mean, and during sleep, we have a metabolic reduction. Part of the... One of perhaps the restorative functions of sleep is to have a metabolic downturn to a degree. But I think the other point is there is... You spoke about all of these different, I'm a multi-system doctor.

And yes, what we find is that all of those different systems, each by themselves, can all independently affect sleep. If you're in inflammation, if you have high blood pressure, if you have abnormal hormonal profiles, if you have poor blood sugar, all of these will disrupt your sleep. So it's feed up to the brain, disrupt sleep, but it also is feed down.

And yes, what we find is that all of those different systems, each by themselves, can all independently affect sleep. If you're in inflammation, if you have high blood pressure, if you have abnormal hormonal profiles, if you have poor blood sugar, all of these will disrupt your sleep. So it's feed up to the brain, disrupt sleep, but it also is feed down.

And yes, what we find is that all of those different systems, each by themselves, can all independently affect sleep. If you're in inflammation, if you have high blood pressure, if you have abnormal hormonal profiles, if you have poor blood sugar, all of these will disrupt your sleep. So it's feed up to the brain, disrupt sleep, but it also is feed down.

And I've often thought, and it works both ways for health and ill health with good sleep versus bad sleep. If you've gone into one of those fancy music studios and there's that mixing deck with all of those little dials on it.