Dr. Matthew Walker
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The story emerged from people who were magnesium deficient, and they had really quite profound sleep problems. And when you made them magnesium normative with supplementation, their sleep got better. That's very different than saying, okay, Matt, we've looked at your blood work. You are magnesium normative. And then taking vast doses of magnesium, I expect to get even better sleep.
The story emerged from people who were magnesium deficient, and they had really quite profound sleep problems. And when you made them magnesium normative with supplementation, their sleep got better. That's very different than saying, okay, Matt, we've looked at your blood work. You are magnesium normative. And then taking vast doses of magnesium, I expect to get even better sleep.
It's not going to happen. It's a little bit like saying you... I tell you, I've got this amazing new blood oxygen saturation machine. It's stunning. And you say, but my blood oxygen saturation is 98, 99%. Do you think that I'm going to push you away? No, you're at ceiling. So you've got to be a bit thoughtful. I think there is a cluster of individuals, the magnesium deficient individuals.
It's not going to happen. It's a little bit like saying you... I tell you, I've got this amazing new blood oxygen saturation machine. It's stunning. And you say, but my blood oxygen saturation is 98, 99%. Do you think that I'm going to push you away? No, you're at ceiling. So you've got to be a bit thoughtful. I think there is a cluster of individuals, the magnesium deficient individuals.
It's not going to happen. It's a little bit like saying you... I tell you, I've got this amazing new blood oxygen saturation machine. It's stunning. And you say, but my blood oxygen saturation is 98, 99%. Do you think that I'm going to push you away? No, you're at ceiling. So you've got to be a bit thoughtful. I think there is a cluster of individuals, the magnesium deficient individuals.
Who will respond to magnesium for sleep. Yeah. Is... If you look at the data, magnesium citrate, not so much. Magnesium oxide certainly does seem to be the more, if there's going to be a form of magnesium that carries the vote so far in the data. Not three and eight, which is bad. Well, I'll come on to three and eight. But magnesium oxide is definitely the one that seems to promote it.
Who will respond to magnesium for sleep. Yeah. Is... If you look at the data, magnesium citrate, not so much. Magnesium oxide certainly does seem to be the more, if there's going to be a form of magnesium that carries the vote so far in the data. Not three and eight, which is bad. Well, I'll come on to three and eight. But magnesium oxide is definitely the one that seems to promote it.
Who will respond to magnesium for sleep. Yeah. Is... If you look at the data, magnesium citrate, not so much. Magnesium oxide certainly does seem to be the more, if there's going to be a form of magnesium that carries the vote so far in the data. Not three and eight, which is bad. Well, I'll come on to three and eight. But magnesium oxide is definitely the one that seems to promote it.
It's just a little tougher on the tummy. And it's harder to absorb. Correct. And it's harder to absorb. Yeah. But I would say that the problem with those two as an explanation, standard forms of magnesium, not magnesium L3 and 8, is that none of those cross the blood-brain barrier. And so if you're thinking magnesium helps your brain to sleep, how could it? Because it doesn't get into the brain.
It's just a little tougher on the tummy. And it's harder to absorb. Correct. And it's harder to absorb. Yeah. But I would say that the problem with those two as an explanation, standard forms of magnesium, not magnesium L3 and 8, is that none of those cross the blood-brain barrier. And so if you're thinking magnesium helps your brain to sleep, how could it? Because it doesn't get into the brain.
It's just a little tougher on the tummy. And it's harder to absorb. Correct. And it's harder to absorb. Yeah. But I would say that the problem with those two as an explanation, standard forms of magnesium, not magnesium L3 and 8, is that none of those cross the blood-brain barrier. And so if you're thinking magnesium helps your brain to sleep, how could it? Because it doesn't get into the brain.
And I think it does it indirectly through relaxation of the body, which sends a signal through the vagus nerve up to your brain to say, you're quiet, you're calm, your body is at peace. And your brain says, great, I'm checking out, it's sleep time. That's the indirect mechanism.
And I think it does it indirectly through relaxation of the body, which sends a signal through the vagus nerve up to your brain to say, you're quiet, you're calm, your body is at peace. And your brain says, great, I'm checking out, it's sleep time. That's the indirect mechanism.
And I think it does it indirectly through relaxation of the body, which sends a signal through the vagus nerve up to your brain to say, you're quiet, you're calm, your body is at peace. And your brain says, great, I'm checking out, it's sleep time. That's the indirect mechanism.
However, there is a form of magnesium, magnesium L3 and eight that based on some animal data from MIT does seem to cross the blood brain barrier. Now there are no randomized control studies that I know of that have looked at magnesium L3 and eight and sleep improvement. So I think the jury is out. If you put a gun to my head and said, which form would you recommend for a patient?
However, there is a form of magnesium, magnesium L3 and eight that based on some animal data from MIT does seem to cross the blood brain barrier. Now there are no randomized control studies that I know of that have looked at magnesium L3 and eight and sleep improvement. So I think the jury is out. If you put a gun to my head and said, which form would you recommend for a patient?
However, there is a form of magnesium, magnesium L3 and eight that based on some animal data from MIT does seem to cross the blood brain barrier. Now there are no randomized control studies that I know of that have looked at magnesium L3 and eight and sleep improvement. So I think the jury is out. If you put a gun to my head and said, which form would you recommend for a patient?
I would probably say magnesium three and eight because at least it's going to potentially get into the brain. So magnesium, I think under certain circumstances, it can be quite useful. I think the data on GABA is not particularly strong right now. So sort of the GABA supplements, I don't think are great. I think theanine has some supportive data to it right now.
I would probably say magnesium three and eight because at least it's going to potentially get into the brain. So magnesium, I think under certain circumstances, it can be quite useful. I think the data on GABA is not particularly strong right now. So sort of the GABA supplements, I don't think are great. I think theanine has some supportive data to it right now.
I would probably say magnesium three and eight because at least it's going to potentially get into the brain. So magnesium, I think under certain circumstances, it can be quite useful. I think the data on GABA is not particularly strong right now. So sort of the GABA supplements, I don't think are great. I think theanine has some supportive data to it right now.