Dr. Michael Greger

Oh, that's a separate, that's a whole separate thing, but this is more inside the cell, the accumulation of debris that contributes to the aging process.

And we can boost autophagy with

exercise, or with fasting.

We can fast or go fast.

Unfortunately, it doesn't really ramp up until 36 to 48 hours of fasting, which really is too long to go unsupervised.

Normally, your kidneys dive into something called sodium conservation mode, such that people can fast literally for months on water only, but

If that response breaks down, then you can suffer a serious electrolyte abnormality, which only manifests with vague symptoms like dizziness or fatigue that could go unnoticed until it's too late.

Really?

So that's why one really should only fast.

If you're fasting over a day, it really should be done under medical supervision.

They can do urine tests.

They can do blood tests.

Just to make sure everything's going to plan.

Uh-huh.

Otherwise, you can run into really serious stress.

So, although we're not going to get that boost and not toughening that short of a time, and you often hear, like, even a few hours, like, time-restricted feeding...

You know, decreasing the feeding window daily, we can improve autophagy.

That's in rodents.

Unfortunately, rodents have these really high metabolisms such that they can lose massive amounts of their body weight in literally a day or two.

In a few days, it can be fatal.