Dr. Mink Chawla
๐ค SpeakerAppearances Over Time
Podcast Appearances
What's more concerning to me is if you have antibodies, why aren't they binding the spike proteins? Yeah. Like that's weird. Right. If you don't have antibodies, okay, fine.
What's more concerning to me is if you have antibodies, why aren't they binding the spike proteins? Yeah. Like that's weird. Right. If you don't have antibodies, okay, fine.
It's possible. That could be part of the reason. The other reason is that there's a clear concept to your original idea about the immune system getting its butt kicked over the years called T-cell exhaustion. Yeah, T-cell exhaustion. That's what Peter and I talked about. Exactly right. And T-cell exhaustion is a very fancy term for saying,
It's possible. That could be part of the reason. The other reason is that there's a clear concept to your original idea about the immune system getting its butt kicked over the years called T-cell exhaustion. Yeah, T-cell exhaustion. That's what Peter and I talked about. Exactly right. And T-cell exhaustion is a very fancy term for saying,
It's possible. That could be part of the reason. The other reason is that there's a clear concept to your original idea about the immune system getting its butt kicked over the years called T-cell exhaustion. Yeah, T-cell exhaustion. That's what Peter and I talked about. Exactly right. And T-cell exhaustion is a very fancy term for saying,
the immune system is seeing so much of the bad guy, it just stops reacting to it. And I'll give you an example of how the body does this. So imagine you go into a gas station and you smell gasoline, which is normal at a gas station. And for whatever reason, you're stuck at the gas station for 35 minutes waiting for somebody.
the immune system is seeing so much of the bad guy, it just stops reacting to it. And I'll give you an example of how the body does this. So imagine you go into a gas station and you smell gasoline, which is normal at a gas station. And for whatever reason, you're stuck at the gas station for 35 minutes waiting for somebody.
the immune system is seeing so much of the bad guy, it just stops reacting to it. And I'll give you an example of how the body does this. So imagine you go into a gas station and you smell gasoline, which is normal at a gas station. And for whatever reason, you're stuck at the gas station for 35 minutes waiting for somebody.
You will notice over 30 minutes, the smell of gas will appear less to you. Right. But the smell of gas has not changed. Just tachyphylaxis. Right. You just start turning off to it. Your immune system does the same thing over time if it sees a lot of antigen for a long time. Wow. It's called T-cell exhaustion. It shuts off. So if you're making too much of anything, too much spike protein, right?
You will notice over 30 minutes, the smell of gas will appear less to you. Right. But the smell of gas has not changed. Just tachyphylaxis. Right. You just start turning off to it. Your immune system does the same thing over time if it sees a lot of antigen for a long time. Wow. It's called T-cell exhaustion. It shuts off. So if you're making too much of anything, too much spike protein, right?
You will notice over 30 minutes, the smell of gas will appear less to you. Right. But the smell of gas has not changed. Just tachyphylaxis. Right. You just start turning off to it. Your immune system does the same thing over time if it sees a lot of antigen for a long time. Wow. It's called T-cell exhaustion. It shuts off. So if you're making too much of anything, too much spike protein, right?
Your immune system just turns off to it. This is what happens in cancer. There's so much cancer. It's different. Your immune system should be screaming and yelling to get after it. Right. It doesn't. Now in the transplantation world, We want this to happen. We want the body to accept the new organ. But we want the immune system to still look for bugs.
Your immune system just turns off to it. This is what happens in cancer. There's so much cancer. It's different. Your immune system should be screaming and yelling to get after it. Right. It doesn't. Now in the transplantation world, We want this to happen. We want the body to accept the new organ. But we want the immune system to still look for bugs.
Your immune system just turns off to it. This is what happens in cancer. There's so much cancer. It's different. Your immune system should be screaming and yelling to get after it. Right. It doesn't. Now in the transplantation world, We want this to happen. We want the body to accept the new organ. But we want the immune system to still look for bugs.
This is a concept called tolerance. So we want the new organ to be tolerated. But that thing that allows tolerance allows you to tolerate things you should not tolerate. Right. And so what we think our filter can do is by removing antigen is to create intolerance. Wow.
This is a concept called tolerance. So we want the new organ to be tolerated. But that thing that allows tolerance allows you to tolerate things you should not tolerate. Right. And so what we think our filter can do is by removing antigen is to create intolerance. Wow.
This is a concept called tolerance. So we want the new organ to be tolerated. But that thing that allows tolerance allows you to tolerate things you should not tolerate. Right. And so what we think our filter can do is by removing antigen is to create intolerance. Wow.
Yeah. A year from today, I aspire to have very high level data. I want your help in developing a spike protein assay that anyone can access. That's easy because right now it's almost impossible to get it. If you're suffering from long COVID, I think one of the big things, and you deal with this in your personal practice, is randomized controlled trial data is our North Star. Right. Right.
Yeah. A year from today, I aspire to have very high level data. I want your help in developing a spike protein assay that anyone can access. That's easy because right now it's almost impossible to get it. If you're suffering from long COVID, I think one of the big things, and you deal with this in your personal practice, is randomized controlled trial data is our North Star. Right. Right.
Yeah. A year from today, I aspire to have very high level data. I want your help in developing a spike protein assay that anyone can access. That's easy because right now it's almost impossible to get it. If you're suffering from long COVID, I think one of the big things, and you deal with this in your personal practice, is randomized controlled trial data is our North Star. Right. Right.