Dr. Mink Chawla
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Podcast Appearances
Yeah, so let's talk about that. So what's really interesting... And I'm not an oncologist, but I thought when you got cancer and you got metastatic cancer, it was a clone thing. So you had this thing in your lung, it gets cloned a billion times, and that same thing that was in your lung is now in your liver, and now it's in your toes, and it's in your brain, it's in your bones, and it's awful.
Yeah, so let's talk about that. So what's really interesting... And I'm not an oncologist, but I thought when you got cancer and you got metastatic cancer, it was a clone thing. So you had this thing in your lung, it gets cloned a billion times, and that same thing that was in your lung is now in your liver, and now it's in your toes, and it's in your brain, it's in your bones, and it's awful.
And that's not exactly what happens. The original tumor is subdividing and mutating at a very high pace. So the cells that go on to metastasize are colonizers. they're not the same as the original parent. So the great, great, great, great, great, great, great grandson is Cortez, a angry colonizing cell.
And that's not exactly what happens. The original tumor is subdividing and mutating at a very high pace. So the cells that go on to metastasize are colonizers. they're not the same as the original parent. So the great, great, great, great, great, great, great grandson is Cortez, a angry colonizing cell.
And that's not exactly what happens. The original tumor is subdividing and mutating at a very high pace. So the cells that go on to metastasize are colonizers. they're not the same as the original parent. So the great, great, great, great, great, great, great grandson is Cortez, a angry colonizing cell.
The cells, because there's an equal number of cells that are indolent and useless, they don't grow up to be big time cancer people. Right. They just die. Right. So the cells that kill you
The cells, because there's an equal number of cells that are indolent and useless, they don't grow up to be big time cancer people. Right. They just die. Right. So the cells that kill you
The cells, because there's an equal number of cells that are indolent and useless, they don't grow up to be big time cancer people. Right. They just die. Right. So the cells that kill you
are not the original so the really smart oncologists say mink you have to chase the met you don't chase the primary you chase the met the metastasis that's right yeah because because the vast majority of cancer deaths come from metastasization 90 of cancer deaths are from metastatic cancer okay and the met looks nothing like the parent so at some point it's got to travel in the That's right.
are not the original so the really smart oncologists say mink you have to chase the met you don't chase the primary you chase the met the metastasis that's right yeah because because the vast majority of cancer deaths come from metastasization 90 of cancer deaths are from metastatic cancer okay and the met looks nothing like the parent so at some point it's got to travel in the That's right.
are not the original so the really smart oncologists say mink you have to chase the met you don't chase the primary you chase the met the metastasis that's right yeah because because the vast majority of cancer deaths come from metastasization 90 of cancer deaths are from metastatic cancer okay and the met looks nothing like the parent so at some point it's got to travel in the That's right.
So when you can remove the cells in the bloodstream, which are the ones doing the metastasizing, we slow down the metastasis. So that was the original thesis. Then we found if you remove the cells, patients feel better.
So when you can remove the cells in the bloodstream, which are the ones doing the metastasizing, we slow down the metastasis. So that was the original thesis. Then we found if you remove the cells, patients feel better.
So when you can remove the cells in the bloodstream, which are the ones doing the metastasizing, we slow down the metastasis. So that was the original thesis. Then we found if you remove the cells, patients feel better.
Because it turns out removing the cells, when you get a bunch of cells that are dying all over the place, because only one in a thousand, one in 10,000 of the cells are active mets. But when they all die, the body's got to mop that up. That's metabolically and energetically very important. It's like a bunch of zombies walking the streets of Miami, getting into traffic, falling into manholes.
Because it turns out removing the cells, when you get a bunch of cells that are dying all over the place, because only one in a thousand, one in 10,000 of the cells are active mets. But when they all die, the body's got to mop that up. That's metabolically and energetically very important. It's like a bunch of zombies walking the streets of Miami, getting into traffic, falling into manholes.
Because it turns out removing the cells, when you get a bunch of cells that are dying all over the place, because only one in a thousand, one in 10,000 of the cells are active mets. But when they all die, the body's got to mop that up. That's metabolically and energetically very important. It's like a bunch of zombies walking the streets of Miami, getting into traffic, falling into manholes.
Someone's got to go clean that stuff up. That's a lot of energy. So one of the things you see in cancer is cachexia. People don't eat because they're metabolically absolutely messed up by the cancer.
Someone's got to go clean that stuff up. That's a lot of energy. So one of the things you see in cancer is cachexia. People don't eat because they're metabolically absolutely messed up by the cancer.
Someone's got to go clean that stuff up. That's a lot of energy. So one of the things you see in cancer is cachexia. People don't eat because they're metabolically absolutely messed up by the cancer.