Dr. Nathan Bryan

And now today, that's recognized as the earliest event in the onset and progression of age-related chronic disease. So my mission is to inform and educate the global population

And now today, that's recognized as the earliest event in the onset and progression of age-related chronic disease. So my mission is to inform and educate the global population

on how important, number one, what nitric oxide is, how it's produced in the human body, what goes wrong in people that can't make it, and then perhaps most importantly, how do we prevent that age-related decline in nitric oxide production so everybody can be empowered to take control of their own health and prevent age-related disease.

on how important, number one, what nitric oxide is, how it's produced in the human body, what goes wrong in people that can't make it, and then perhaps most importantly, how do we prevent that age-related decline in nitric oxide production so everybody can be empowered to take control of their own health and prevent age-related disease.

And that's what the science tells us, but as you illustrated, most people have never heard of this.

And that's what the science tells us, but as you illustrated, most people have never heard of this.

Well, you know, if you look at population-based studies at different age groups, we see about a 10% to 12% decline in what we call endothelial function per decade. So nitric oxide is a gas. It's produced in the endothelium. So the endothelium is the single layer of cells that line every blood vessel throughout the body.

Well, you know, if you look at population-based studies at different age groups, we see about a 10% to 12% decline in what we call endothelial function per decade. So nitric oxide is a gas. It's produced in the endothelium. So the endothelium is the single layer of cells that line every blood vessel throughout the body.

So the function of these endothelial cells is to regulate vascular tone and to regulate solute exchange and extravasation or transport of molecules across that endothelial layer.

So the function of these endothelial cells is to regulate vascular tone and to regulate solute exchange and extravasation or transport of molecules across that endothelial layer.

And so when your endothelial cells can no longer make nitric oxide gas, they no longer dilate, so the blood vessels become constricted, you start to get inflammation, you get stiff arteries, plaque deposition, and that's what starts cardiovascular disease or atherosclerosis.

And so when your endothelial cells can no longer make nitric oxide gas, they no longer dilate, so the blood vessels become constricted, you start to get inflammation, you get stiff arteries, plaque deposition, and that's what starts cardiovascular disease or atherosclerosis.

Well, we know there's a hierarchy, right? So the first sign and symptom of nitric oxide deficiency is usually erectile dysfunction. And when you think about this, when we're stimulated or we're about to have intimacy with our partner, we have to dilate the blood vessels.

Well, we know there's a hierarchy, right? So the first sign and symptom of nitric oxide deficiency is usually erectile dysfunction. And when you think about this, when we're stimulated or we're about to have intimacy with our partner, we have to dilate the blood vessels.

So when erections in both men and women are dependent upon dilation of the blood vessels to get engorgement, to get increase in blood flow, and that's what an erection is. But if those blood vessels can't make nitric oxide, the blood vessels don't dilate, so there's no increase in blood flow, there's no engorgement, and that's by definition what we call erectile dysfunction.

So when erections in both men and women are dependent upon dilation of the blood vessels to get engorgement, to get increase in blood flow, and that's what an erection is. But if those blood vessels can't make nitric oxide, the blood vessels don't dilate, so there's no increase in blood flow, there's no engorgement, and that's by definition what we call erectile dysfunction.

And it's the same in men and women, right? Whether it's the penis or the clitoris or the labia, you have to have an increase in blood flow. And without nitric oxide, there's no increase in blood flow. So that's number one. And we call that the canary in the coal mine. Because for years, people thought it was a lifestyle disorder, right?

And it's the same in men and women, right? Whether it's the penis or the clitoris or the labia, you have to have an increase in blood flow. And without nitric oxide, there's no increase in blood flow. So that's number one. And we call that the canary in the coal mine. Because for years, people thought it was a lifestyle disorder, right?

But now it's recognized that it's a symptom of loss of nitric oxide and really an accelerated form of cardiovascular disease. So we have to focus on the vascular component of erectile dysfunction.

But now it's recognized that it's a symptom of loss of nitric oxide and really an accelerated form of cardiovascular disease. So we have to focus on the vascular component of erectile dysfunction.