Dr. Nathan Bryan
👤 PersonAppearances Over Time
Podcast Appearances
And so what we've done, and we've been working on this for probably six years, trying to figure out, I know in dental medicine, you have to eradicate the oral pathogens. But more importantly, we have to support the healthy microbiome. And that's why, you know, it took me five or six years to develop a toothpaste because what's the purpose of toothpaste?
Clean the teeth, clean the biofilms on the teeth, give the body the minerals it needs to enhance mineral density of the teeth, maintain healthy gums and normal pH, but more importantly, support the oral microbiome. And how do you do that?
Clean the teeth, clean the biofilms on the teeth, give the body the minerals it needs to enhance mineral density of the teeth, maintain healthy gums and normal pH, but more importantly, support the oral microbiome. And how do you do that?
Clean the teeth, clean the biofilms on the teeth, give the body the minerals it needs to enhance mineral density of the teeth, maintain healthy gums and normal pH, but more importantly, support the oral microbiome. And how do you do that?
Well, you create a toothpaste that's free of any kind of detergents, fluorides, antiseptics, but then create an environment after you brush your teeth that supports the repopulation of the healthy microbiome, improve the diversity of the microbiome, normalize the pH, and that's through our oral care products.
Well, you create a toothpaste that's free of any kind of detergents, fluorides, antiseptics, but then create an environment after you brush your teeth that supports the repopulation of the healthy microbiome, improve the diversity of the microbiome, normalize the pH, and that's through our oral care products.
Well, you create a toothpaste that's free of any kind of detergents, fluorides, antiseptics, but then create an environment after you brush your teeth that supports the repopulation of the healthy microbiome, improve the diversity of the microbiome, normalize the pH, and that's through our oral care products.
So we're developing a nitric oxide-friendly toothpaste and a nitric oxide-friendly mouth rinse.
So we're developing a nitric oxide-friendly toothpaste and a nitric oxide-friendly mouth rinse.
So we're developing a nitric oxide-friendly toothpaste and a nitric oxide-friendly mouth rinse.
You know, I was the person who developed these strips. Wow. In 2009, I developed these salivary test strips and created this kind of semi-quantitative colorimetric test strips. I filed patents on them when I was a professor at UT Medical School in Houston. Years later, we abandoned the patents because this chemistry that we're capturing on this test strip is old chemistry.
You know, I was the person who developed these strips. Wow. In 2009, I developed these salivary test strips and created this kind of semi-quantitative colorimetric test strips. I filed patents on them when I was a professor at UT Medical School in Houston. Years later, we abandoned the patents because this chemistry that we're capturing on this test strip is old chemistry.
You know, I was the person who developed these strips. Wow. In 2009, I developed these salivary test strips and created this kind of semi-quantitative colorimetric test strips. I filed patents on them when I was a professor at UT Medical School in Houston. Years later, we abandoned the patents because this chemistry that we're capturing on this test strip is old chemistry.
It's called the grease reaction. Grease. The grease. G-R-I-E-S-S. Okay. It was named after, I think, a chemist who developed that. It's a diazonium salt that forms that turns a pink color. So we can absorb it. We can detect it at 540 nanometers. So it should turn pink. And it's basically an acidified sulfanilamide reaction with nitrite.
It's called the grease reaction. Grease. The grease. G-R-I-E-S-S. Okay. It was named after, I think, a chemist who developed that. It's a diazonium salt that forms that turns a pink color. So we can absorb it. We can detect it at 540 nanometers. So it should turn pink. And it's basically an acidified sulfanilamide reaction with nitrite.
It's called the grease reaction. Grease. The grease. G-R-I-E-S-S. Okay. It was named after, I think, a chemist who developed that. It's a diazonium salt that forms that turns a pink color. So we can absorb it. We can detect it at 540 nanometers. So it should turn pink. And it's basically an acidified sulfanilamide reaction with nitrite.
Very complex chemistry, but it creates this colorimetric reaction that we can quantify. The reason that I abandoned the patents and the reason that I don't rely on them anymore is because there's false positives. So there's really no false negative. And really at the end of the day, when people understand what we're measuring and what it means, then I think they can provide value.
Very complex chemistry, but it creates this colorimetric reaction that we can quantify. The reason that I abandoned the patents and the reason that I don't rely on them anymore is because there's false positives. So there's really no false negative. And really at the end of the day, when people understand what we're measuring and what it means, then I think they can provide value.
Very complex chemistry, but it creates this colorimetric reaction that we can quantify. The reason that I abandoned the patents and the reason that I don't rely on them anymore is because there's false positives. So there's really no false negative. And really at the end of the day, when people understand what we're measuring and what it means, then I think they can provide value.
But people would use this test strip and think, oh, this is nitric oxide test strip. It's not a nitric oxide test strip. Nitric oxide is a gas. Once it's produced, it's gone in less than a second. What we're measuring here is salivary nitrite and the ability of the oral microbiome to recycle nitrate from the diet into nitrite. Then we swallow the nitrite in our saliva.