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Dr. Peter Attia

👤 Speaker
11186 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Put a black box label on it and we should all still have access to Merck's.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Put a black box label on it and we should all still have access to Merck's.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

The baby got thrown out with the bathwater on that one.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

The baby got thrown out with the bathwater on that one.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Why do you think there hasn't been any drug that's come close to that? Like Celebrex is a joke. Like none of the drugs that are in the...

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Why do you think there hasn't been any drug that's come close to that? Like Celebrex is a joke. Like none of the drugs that are in the...

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Do you have a version on dose? I mean, do you say 800 milligrams of ibuprofen TID three times a day, 2400 milligrams would be, you would tolerate that for how many days if a person needed it? Week to two weeks on that.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Do you have a version on dose? I mean, do you say 800 milligrams of ibuprofen TID three times a day, 2400 milligrams would be, you would tolerate that for how many days if a person needed it? Week to two weeks on that.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

You're eating. Yeah.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

You're eating. Yeah.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Yeah, it is interesting that we can buy acetaminophen and ibuprofen over the counter, and yet they can cause a ton of damage if not taken correctly.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Yeah, it is interesting that we can buy acetaminophen and ibuprofen over the counter, and yet they can cause a ton of damage if not taken correctly.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Liver failure. Let's talk about acetaminophen for a while. When I last tried to understand it, there was no clue as to how it worked. To this day, do we understand how it works?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Liver failure. Let's talk about acetaminophen for a while. When I last tried to understand it, there was no clue as to how it worked. To this day, do we understand how it works?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

But there's a nice synergy with acetaminophen and ibuprofen because different mechanism of action, different organ systems are impacted. So you can take less of each when you combine them. What's your take on that?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

But there's a nice synergy with acetaminophen and ibuprofen because different mechanism of action, different organ systems are impacted. So you can take less of each when you combine them. What's your take on that?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Yeah. My go-to stack, if I am actually in pain, a year ago, I had to get a crown put on a tooth that had an old filling that broke. And it's the funniest thing because of how remarkable the teeth are at sensation, but the crown was a little too high. Okay, so what's the impact of that? That meant every time I took a bite, that one tooth was bearing the brunt of it.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Yeah. My go-to stack, if I am actually in pain, a year ago, I had to get a crown put on a tooth that had an old filling that broke. And it's the funniest thing because of how remarkable the teeth are at sensation, but the crown was a little too high. Okay, so what's the impact of that? That meant every time I took a bite, that one tooth was bearing the brunt of it.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

It was the last tooth I had right in front of my wisdom tooth. And I'm talking to my dentist and he's like, yeah, Peter, it's just too high. Just come in and let me shave a little bit of it off. Well, I didn't have the time to go in. So for two months, I did not go in to get this thing shaved off. The pain was, this is how stupid I am.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

It was the last tooth I had right in front of my wisdom tooth. And I'm talking to my dentist and he's like, yeah, Peter, it's just too high. Just come in and let me shave a little bit of it off. Well, I didn't have the time to go in. So for two months, I did not go in to get this thing shaved off. The pain was, this is how stupid I am.