Dr. Rachel Rubin

The worse your hot flashes, the worse your risk of cardiovascular issues and things like that. Joint pain is a huge one. I never thought as a urologist I would treat so much joint pain. Never in a million years did I think I cared about joint pain. And yet patients come in all the time and say, oh, my God, I don't get out of bed feeling old. I don't feel creaky.

The worse your hot flashes, the worse your risk of cardiovascular issues and things like that. Joint pain is a huge one. I never thought as a urologist I would treat so much joint pain. Never in a million years did I think I cared about joint pain. And yet patients come in all the time and say, oh, my God, I don't get out of bed feeling old. I don't feel creaky.

My joints recover again after I exercise. Again, empty gas tank inflammation. I think hormones are nature's joint fluid, if you will. So almost like brake fluid. Go back to the car analogy.

My joints recover again after I exercise. Again, empty gas tank inflammation. I think hormones are nature's joint fluid, if you will. So almost like brake fluid. Go back to the car analogy.

So it's really cool. So your eyes need lubrication. Your ears need wax. Your vagina needs lubrication. Your joints actually need lubrication. And so think of horny teenager. You've got oils, oily skin. So hormones create these oils, vaginal lubrication, oil for your skin. There are androgen receptors in your eyeballs, right, in these myobian glands. So I think of hormones like fluid.

So it's really cool. So your eyes need lubrication. Your ears need wax. Your vagina needs lubrication. Your joints actually need lubrication. And so think of horny teenager. You've got oils, oily skin. So hormones create these oils, vaginal lubrication, oil for your skin. There are androgen receptors in your eyeballs, right, in these myobian glands. So I think of hormones like fluid.

So as you lose the hormones or the hormones go too high or too low, it dries everything out. And so you get joint pain, you get frozen shoulder, you get plantar fasciitis. And now it was recently published on by my colleague Vonda Wright, the musculoskeletal syndrome of menopause. This idea that so many women in their 40s and 50s, everything starts to break down.

So as you lose the hormones or the hormones go too high or too low, it dries everything out. And so you get joint pain, you get frozen shoulder, you get plantar fasciitis. And now it was recently published on by my colleague Vonda Wright, the musculoskeletal syndrome of menopause. This idea that so many women in their 40s and 50s, everything starts to break down.

It's because the gas tank is empty and that inflammation increases. It's such a simple analogy. So what are the symptoms you've got? Musculoskeletal symptoms, sleep issues, mood issues, bleeding changes, obviously low libido, orgasm problems, arousal problems, pain with sex increases like crazy. I sent you a list here. What am I missing? You've got a list there.

It's because the gas tank is empty and that inflammation increases. It's such a simple analogy. So what are the symptoms you've got? Musculoskeletal symptoms, sleep issues, mood issues, bleeding changes, obviously low libido, orgasm problems, arousal problems, pain with sex increases like crazy. I sent you a list here. What am I missing? You've got a list there.

It's one of the most common symptoms. All women start going to doctors in their 40s. Like doctors, I know you're listening and you get so many people and every day you say, oh, it's probably hormonal, but you're not giving them the solution. You're just telling them it's not cancer. So the neurologists are seeing all these patients to rule out cognitive decline or all these other issues.

It's one of the most common symptoms. All women start going to doctors in their 40s. Like doctors, I know you're listening and you get so many people and every day you say, oh, it's probably hormonal, but you're not giving them the solution. You're just telling them it's not cancer. So the neurologists are seeing all these patients to rule out cognitive decline or all these other issues.

But really, it's that brain fog because your brain is filled with estrogen receptors. This is crazy research. OK, I don't know if you've had Lisa Moscone on, but here's this researcher from Cornell, neuroscience researcher, who says, hey, I want to study Alzheimer's. I want to do this. This is just in the last couple of years.

But really, it's that brain fog because your brain is filled with estrogen receptors. This is crazy research. OK, I don't know if you've had Lisa Moscone on, but here's this researcher from Cornell, neuroscience researcher, who says, hey, I want to study Alzheimer's. I want to do this. This is just in the last couple of years.

And she goes to her lab manager and says, OK, what's the assay for estradiol in the brain? I need to look at estradiol receptors in the brain. And the people at Cornell was like, that doesn't exist. She's like, what do you mean that doesn't exist? She's like, how can we not look at estrogen receptors in the brain?

And she goes to her lab manager and says, OK, what's the assay for estradiol in the brain? I need to look at estradiol receptors in the brain. And the people at Cornell was like, that doesn't exist. She's like, what do you mean that doesn't exist? She's like, how can we not look at estrogen receptors in the brain?

So she gets Maria Shriver to give her a giant amount of money, who gives her a huge amount of money. So she now develops this assay. This is only within the last couple of years. She just published in Nature, very early findings. What would you expect? Your body is efficient. It's not going to do things it doesn't need to do.

So she gets Maria Shriver to give her a giant amount of money, who gives her a huge amount of money. So she now develops this assay. This is only within the last couple of years. She just published in Nature, very early findings. What would you expect? Your body is efficient. It's not going to do things it doesn't need to do.

So the hypothesis was that as menopause gets later and later, the estrogen receptors in your brain are going to downregulate. Why have receptors around when there's no estrogen to feed the brain? What did she find? The exact opposite. That actually, even up to 65, she stopped looking past 65 because she's like, there's no way that's going to matter.

So the hypothesis was that as menopause gets later and later, the estrogen receptors in your brain are going to downregulate. Why have receptors around when there's no estrogen to feed the brain? What did she find? The exact opposite. That actually, even up to 65, she stopped looking past 65 because she's like, there's no way that's going to matter.