Dr. Rachel Rubin

And what's so fascinating is we know that the vagina, the vulvar vestibule, the clitoris, the bladder have androgen receptors. So us using just estrogen in this tissue may be missing the whole point. We do have patients that benefit from having an androgen in the tissue as well. And the only FDA approved product we have is Intrarosa, which is vaginal DHEA. Now, it's often hard to get for patients.

And what's so fascinating is we know that the vagina, the vulvar vestibule, the clitoris, the bladder have androgen receptors. So us using just estrogen in this tissue may be missing the whole point. We do have patients that benefit from having an androgen in the tissue as well. And the only FDA approved product we have is Intrarosa, which is vaginal DHEA. Now, it's often hard to get for patients.

If I could get it for everybody, I would. It's fabulous because the tissue needs androgens. The data is very good.

If I could get it for everybody, I would. It's fabulous because the tissue needs androgens. The data is very good.

So there is some data, not a lot, but there's data that shows someone with urgency, give them vaginal estrogen, switch them to DHEA. It'll help those people who still have urgency.

So there is some data, not a lot, but there's data that shows someone with urgency, give them vaginal estrogen, switch them to DHEA. It'll help those people who still have urgency.

We published on this. So we just published in the Menopause Journal that it shows the same decreased risk of UTIs by more than half. So that was a very proud publication that we just put out. We use it frequently. What's nice about the product, it's a nightly product. It's DHEA and palm oil. So it's very moisturizing, very lubricating.

We published on this. So we just published in the Menopause Journal that it shows the same decreased risk of UTIs by more than half. So that was a very proud publication that we just put out. We use it frequently. What's nice about the product, it's a nightly product. It's DHEA and palm oil. So it's very moisturizing, very lubricating.

And my mentor, Erwin Goldstein, published that actually it also helps the tissue called the vulvar vestibule. Do you know what the vulvar vestibule is?

And my mentor, Erwin Goldstein, published that actually it also helps the tissue called the vulvar vestibule. Do you know what the vulvar vestibule is?

So I'm obsessed with homologues. Homologues are sort of this idea of, I'll give you an example. The penis and the clitoris are exactly the same thing. Yes, yes, sorry. No, no, no, that's okay. They're homologues of each other, right? The head of the penis and the head of the clitoris, homologues. So it's what part of the body in one is the same in the other.

So I'm obsessed with homologues. Homologues are sort of this idea of, I'll give you an example. The penis and the clitoris are exactly the same thing. Yes, yes, sorry. No, no, no, that's okay. They're homologues of each other, right? The head of the penis and the head of the clitoris, homologues. So it's what part of the body in one is the same in the other.

So the homologue of the scrotal skin is the labia majora. Okay. You're with me. The prepuce or the hood, the clitoris and the penis both have a prepuce or a hood to it. So there's a line that goes down a penis that goes down the penis and the scrotum. Do you remember what that's called? Median- Raph. Yeah. You got it. Raphay.

So the homologue of the scrotal skin is the labia majora. Okay. You're with me. The prepuce or the hood, the clitoris and the penis both have a prepuce or a hood to it. So there's a line that goes down a penis that goes down the penis and the scrotum. Do you remember what that's called? Median- Raph. Yeah. You got it. Raphay.

Okay. So the median raphay is the line that goes down the penis and the scrotum, straight line right in the middle. What's the homologue in the vulva? I just learned this.

Okay. So the median raphay is the line that goes down the penis and the scrotum, straight line right in the middle. What's the homologue in the vulva? I just learned this.

No. No.

No. No.

Close. Labia minora.

Close. Labia minora.