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Dr. Rachel Rubin

👤 Person
698 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You may give them extra life from a breast cancer perspective, but you are shortening their life from a bone health and a cardiovascular disease perspective. That is very clear. So the other problem is the DCIS. If you are not going to give someone endocrine therapy of any kind and they're done, they have surgery, they're done, there is no reason why they can't take hormone therapy.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You may give them extra life from a breast cancer perspective, but you are shortening their life from a bone health and a cardiovascular disease perspective. That is very clear. So the other problem is the DCIS. If you are not going to give someone endocrine therapy of any kind and they're done, they have surgery, they're done, there is no reason why they can't take hormone therapy.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And then when it comes to active breast cancer, there is a lot of emerging questioning in this patient population. And again, the question is, if you're allowed to get pregnant, are you allowed to take hormone therapy? And that's really the pushback that we give some people. And I think there's a lot of data that we need here, but we need to be asking these questions. I'm a urologist.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And then when it comes to active breast cancer, there is a lot of emerging questioning in this patient population. And again, the question is, if you're allowed to get pregnant, are you allowed to take hormone therapy? And that's really the pushback that we give some people. And I think there's a lot of data that we need here, but we need to be asking these questions. I'm a urologist.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

When I came out of my training, it was testosterone fuels prostate cancer. Now, 10 years later, it's you have prostate cancer. Sure, we can give you testosterone. No problem. If you have metastatic disease, we target testosterone. So we're going to use castration level androgen blockers. But that doesn't mean if you have localized disease that you can't have testosterone therapy.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

When I came out of my training, it was testosterone fuels prostate cancer. Now, 10 years later, it's you have prostate cancer. Sure, we can give you testosterone. No problem. If you have metastatic disease, we target testosterone. So we're going to use castration level androgen blockers. But that doesn't mean if you have localized disease that you can't have testosterone therapy.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

So we think of testosterone and prostate cancer as a saturation model concept. And I actually think we need to be using that model potentially when it comes to breast cancer and have more logic and understanding and less fear. It's marketing. All prostate cancer...

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

So we think of testosterone and prostate cancer as a saturation model concept. And I actually think we need to be using that model potentially when it comes to breast cancer and have more logic and understanding and less fear. It's marketing. All prostate cancer...

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

is testosterone-sensitive prostate cancer, but we don't cut off testicles for the fear that an abnormal cell will happen in a prostate. A lot of breast cancer is estrogen-receptive breast cancer, not all of it, right? But some of it is. That doesn't mean estrogen causes cancer.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

is testosterone-sensitive prostate cancer, but we don't cut off testicles for the fear that an abnormal cell will happen in a prostate. A lot of breast cancer is estrogen-receptive breast cancer, not all of it, right? But some of it is. That doesn't mean estrogen causes cancer.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And this is, again, where that patriarchal divide happens is we're willing to take those risks and focus on quality of life when it comes to men's health. We castrate women with the mere thought that they may develop an abnormal cell in their body and completely ignore their quality of life and all of those things that go with it. And women are more than breast tissue.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And this is, again, where that patriarchal divide happens is we're willing to take those risks and focus on quality of life when it comes to men's health. We castrate women with the mere thought that they may develop an abnormal cell in their body and completely ignore their quality of life and all of those things that go with it. And women are more than breast tissue.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They are so much more than their cancer risk. And we have to understand and actually have these reasonable conversations with with women. And what I say is your oncologist is not in charge of you. They give you advice. It's like a pit crew. Let's go back to our car model. You have a pit crew, but you get to decide who's on your pit crew and who fits into your pit crew.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They are so much more than their cancer risk. And we have to understand and actually have these reasonable conversations with with women. And what I say is your oncologist is not in charge of you. They give you advice. It's like a pit crew. Let's go back to our car model. You have a pit crew, but you get to decide who's on your pit crew and who fits into your pit crew.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

But it can't be just one doctor. You may need someone to talk about your sexual health. You may need someone to talk about your menopause hormones. You may need a bone doctor. You may need a heart doctor. So you need to collect your pit crew. But when one doctor says, no, you can't do this with your body, I don't like that terminal. I don't think it's fair anymore.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

But it can't be just one doctor. You may need someone to talk about your sexual health. You may need someone to talk about your menopause hormones. You may need a bone doctor. You may need a heart doctor. So you need to collect your pit crew. But when one doctor says, no, you can't do this with your body, I don't like that terminal. I don't think it's fair anymore.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And when you give women information about how their bodies work, they make great decisions for themselves. They can look at the menu and say, listen, I'm most worried about Alzheimer's and I've looked at the data and this is what I choose to do. Or, hey, I'm more worried about osteoporosis. Listen, my grandma broke a bunch of ribs. She had Alzheimer's and osteoporosis.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And when you give women information about how their bodies work, they make great decisions for themselves. They can look at the menu and say, listen, I'm most worried about Alzheimer's and I've looked at the data and this is what I choose to do. Or, hey, I'm more worried about osteoporosis. Listen, my grandma broke a bunch of ribs. She had Alzheimer's and osteoporosis.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And my grandpa hugged her and she broke a bunch of ribs. That's not how I want to age. So what do I care about? I don't want to get osteoporosis. I don't want to get dementia. And I've seen all the literature. Hormone therapy sounds pretty good to me. And that's really the key. I think there's a lot of people on social media, maybe negative about hormone therapy.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And my grandpa hugged her and she broke a bunch of ribs. That's not how I want to age. So what do I care about? I don't want to get osteoporosis. I don't want to get dementia. And I've seen all the literature. Hormone therapy sounds pretty good to me. And that's really the key. I think there's a lot of people on social media, maybe negative about hormone therapy.