Dr. Rhonda Patrick

If you calorie restrict, that's the first thing that goes.

And it really does help reset the system.

When people first start an intermittent fasting protocol, if they've never done it, it can be challenging because they're not what's called metabolically flexible.

So that means that essentially your body is really capable of using fatty acids as energy to make ketone bodies.

This is something that's a very sort of clean source of energy that's used.

It's great for the brain.

But if you've never really fasted, if you're constantly grazing, you're eating and you don't exercise because exercise also can

make you metabolically flexible, then your body isn't used to it.

And it's a little bit of an activation energy.

You have to kind of push past it.

It's a little bit more challenging, but your body adapts.

And so after a couple of weeks, guess what?

Like if you're intermittent fasting and there's a lot of ways to do that.

So, you know, let's say you skip a meal, then you're not like, I haven't eaten anything today, you know, yet.

And I usually eat my first meal around noon.

I do mostly every day a week, yeah.

But I'm not hungry until noon because your body adapts.

And ketone bodies, which are what are made when you're basically metabolizing fatty acids for fuel.

rather than glucose is those ketones like beta hydroxybutyrate, they're satiating, you're satiated.

And so it takes a person, we can store glucose in our liver as glycogen and you have to be fasted for anywhere between 12 to 36 hours