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Dr. Rhonda Patrick

๐Ÿ‘ค Speaker
6660 total appearances

Appearances Over Time

Podcast Appearances

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

Skeletal muscle makes up around 30 to 40% of our lean body mass.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

More muscle doesn't just mean more strength.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

It means better metabolism, enhanced insulin sensitivity, and a pretty good defense against type 2 diabetes.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

It also dramatically decreases frailty and the risk for sarcopenia, one of the main risk factors for falls and fractures in older adults.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

Research has shown that individuals who suffer from a fragility fracture are twice as likely to die compared to those without such fractures.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

And between 22 to 58 percent of people with a hip fracture pass away within just 12 months after the injury.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

In old age, falling and breaking a hip can literally be a death sentence.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

A better body composition dramatically improves quality of life and reduces disability risk.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

There are a few factors that play a role in this, but a big player here is a phenomenon called

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

anabolic resistance.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

So as we age, our muscles become less responsive to amino acids, meaning they don't trigger muscle protein synthesis in response to protein intake as effectively.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

So for older individuals, the same amount of protein results in a smaller increase in muscle protein synthesis compared to younger people.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

Some studies have shown that an older person requires almost twice as much protein for the same response.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

For example, around 0.24 grams of protein per kilogram body weight or 0.1 grams per pound.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

That's 20 grams of protein for about an 80 kilogram man.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

maximally stimulates muscle protein synthesis in someone young.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

But this dose is higher for older adults who need about 0.4 grams of protein per kilogram or 0.18 grams per pound of protein per dose.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

An older adult man weighing about 80 kilograms would need about 32 grams of protein to maximally stimulate muscle protein synthesis.

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

By the way, for anyone taking notes, this suggests

FoundMyFitness
#097 The Science of Protein and Its Role in Longevity, Cancer, Aging, and Building Muscle

that the optimal amount of protein per dose is between 20 and as high as 35 grams of protein, depending on your personal level of anabolic resistance.