Dr. Rhonda Patrick

see that their testosterone is like on the lower end of the normal reference range and like want to do something about it like with respect to like not skipping over the lifestyle factors and just like I'm going to go straight into like I'm just going to take some testosterone right and I think that would be the case to avoid right if you're not especially not really having symptoms but you're just kind of like freaked out by the numbers right.

Right.

Yeah.

Okay.

So let's talk about some of the important risks that, you know, people should keep in mind when they're going to start testosterone replacement therapy.

I know you've like talked about this, heard about it, like the cardiovascular disease risk.

I mean, for a while it was a controversy, right?

Like doing testosterone replacement therapy is going to increase your cardiovascular disease risk.

Yeah.

there's the Traverse trial that's kind of, we got some pre-data here where it seems as though, this is a very large trial, placebo-controlled, where it seems as though men, these are older men that were, at least it seems to be hypogonadal, like they were low testosterone.

And if they were given testosterone replacement therapy to a normal physiological restoration range,

there's no really adverse effects on cardiovascular outcomes.

What's the thought here with respect to cardiovascular disease risk?

No, this is so important.

And that's kind of why I was like, these are hypogonadal.

And, you know, it's like, I guess their normal physiological range is not really accurate if it's only going to like 400.

So basically, you're just making a non-hypogonadal.

But it is important because you mentioned erythroporesis.

And so this is another kind of concern.

you know, with testosterone, which does regulate red blood cell production, it does increase, you know, the thickness of blood.