Dr. Rhonda Patrick

I like to do body weight squats.

That's something that I'll, you know, try to do after a meal, particularly when I'm on vacation and get the gelato that I never, ever, ever eat unless I'm in Rome.

But okay.

Well, that's great.

So many people ask about these supplements and, you know, are there these supplements that can improve insulin sensitivity?

So they

You know, you hear everything from magnesium to alpha-lipoic acid to berberine, apple cider vinegar.

And if there's any merit to that or taking it before a meal or is this just like dropping like a drop of water in the pool to like try to fill the pool up?

That's fascinating because when you're talking about the short chain fatty acid, you know, and I'm thinking, you know, acetate.

Yep.

So acetate, acetic acid, we're going from acid base.

I'm thinking of lactate, lactic acid, lactate, and that's when you're generating with exercise and lactate signaling.

is to AMP kinase, it's very much, you know, and then I'm thinking, well, is this like a short chain fatty acid sort of like, because they're signaling molecules, right?

They are.

And is there something that would be so interesting to look at to see if there's something going on with lactate, acetate, malate, right?

Like that's in like a Granny Smith apple or something like that, more sour apple, right?

Yep.

I mean, all these different short chain fatty acids, well, the short chain fatty acids that you're getting from foods, and then there's another, malate's also in like blueberries, right?

malic acid, malic acids in them.

So my wheels are turning here when you're mentioning that because it'd be so fascinating to see if there's a common mechanism.